ID A0A3Q1AZK0_AMPOC Unreviewed; 1324 AA.
AC A0A3Q1AZK0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Multiple EGF like domains 6 {ECO:0000313|Ensembl:ENSAOCP00000003271.1};
GN Name=MEGF6 {ECO:0000313|Ensembl:ENSAOCP00000003271.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000003271.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000003271.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR STRING; 80972.ENSAOCP00000003271; -.
DR Ensembl; ENSAOCT00000010071.1; ENSAOCP00000003271.1; ENSAOCG00000006605.1.
DR GeneTree; ENSGT00940000156971; -.
DR OMA; HLCEHCP; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR Gene3D; 2.10.25.10; Laminin; 7.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 7.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR24035; MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN; 1.
DR Pfam; PF07645; EGF_CA; 2.
DR Pfam; PF14670; FXa_inhibition; 3.
DR Pfam; PF12661; hEGF; 4.
DR Pfam; PF00053; Laminin_EGF; 10.
DR PRINTS; PR00011; EGFLAMININ.
DR PRINTS; PR00907; THRMBOMODULN.
DR SMART; SM00181; EGF; 27.
DR SMART; SM00179; EGF_CA; 6.
DR SMART; SM00180; EGF_Lam; 20.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 16.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 8.
DR PROSITE; PS01248; EGF_LAM_1; 5.
DR PROSITE; PS50027; EGF_LAM_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Laminin EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00460};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..1324
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018732319"
FT DOMAIN 55..95
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 422..457
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 514..556
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 637..668
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 802..837
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 845..880
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 973..1003
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1165..1200
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1207..1242
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 447..456
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 533..542
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 658..667
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 827..836
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 870..879
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 993..1002
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1190..1199
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1232..1241
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1324 AA; 141176 MW; 1ADE08D6E3DAA405 CRC64;
MALSSERWML FLVIIEVMAC LTSAANYPHS YYRRICYRPH CYHGYHSYNL GYLASIDECQ
VHNGGCQHRC INTRGSYYCE CHPGSRLHVD GRTCLVHSCA IGNGGCEHYC VQQSVAHFRC
RCKPNYALAE DGKHCKQNPC ADQNGGCMHE CRVDGGRAHC DCKVGYVLTE DAKTVDECET
EEANCAHGCH NTLGSYACVC NAAYELGSDG KQCYIEMEIV NSCENNNGGC SHRCQHSTSG
PVCSCNHGYR LDDDLKTCVV DECGEQSSCC EQDCTNYPGG YECYCSAGYR LNSDGCSVDE
CLAANGGCDH TCQNSAGSFQ CFCRRGFRLD EDRQSCIPQL TLLQDYSQPL ERYDDYEDDE
GELRAESNLA EKFCLDDTFG HDCSLTCDDC SNGGKCNLWK NGCDCPDGWT GIICNQCPEG
HFGKNCSFHC KCKNGASCDA VSGSCRCPPG VSGDLCQDCP KGFYGKQCNK KCNCANNGRC
HRTYGACLCD PGLYGRFCHL CPKWTFGPGC SEECQCDQQH TQECHRRHGT CVCKPGYQGN
TCKECRPGTY GAGCEKKCSC PPGVSCDHVT GDCQRKCPAG RHGENCDQCP EGRFGTGCIR
PCNCTGAPCD KVTGQCQCPA GTLGKHCPEG FWGPGCTETC PLCENGGVCD KHNGSCNCPA
GFMGRLCQNC PGGRFGEGCQ MKCVCENNAH CDPVSGRCTC ATGWTGHTCR KCDAGHWGTD
CAQTCDCRNG DGSCDAATGQ CNCEAGFTGA HCHQCPAGMF GLGCRHRCQC DNKALCDHVS
GACTCQVGWT GTFCEKCPQG FFGLDCQEKC LCLNGGSCDH VSGVCSCPAG WIGPFCNLAC
PAGFYGEGCN QTCSCRNDGI CHPASGQCVC TSGWMGPNCT QCPAGFYGAD CRQRCLCQNG
ATCNKTSGKC TCASGWTGTA CVSGRFGADC QQQCECENGS QCDRQTGQCS CSSGWIGERC
EKCEAGLFGA GCEERCQCVH GASCHHITGE CQCPPGWRGK LCDKCLPGTF GKSCMQRCSC
VQGTSCHHVS GECGCPPGFT GNGCEQCLPG TFGQNCNQVC QCSETNQLCH PVSGSCYCAP
GFHGLKCDQC PAGRYGVDCA RVALCGDGAQ NNPVTGRCPP GWFGADCAHR CNCSNGGACD
SATGNCTCGL GWTGAHCNTC PAGRYGANCQ LKCNCQNDGA CDRVMGTCQC SPGYYGHLCE
HCPAGLHGPL CQLQCDCLNG ASCHPVSGLC ICPPGYHGAH CHRCEQGSYG QGCGKVCDCE
GDTPCDPVTG RCLCSSGKTG PRCDICGVNR FGPDCSETCR CENGAQCDRR NGRCICLHSW
IGLS
//
