ID   A0A3Q1B968_AMPOC        Unreviewed;       209 AA.
AC   A0A3Q1B968;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=exodeoxyribonuclease III {ECO:0000256|ARBA:ARBA00012115};
DE            EC=3.1.11.2 {ECO:0000256|ARBA:ARBA00012115};
OS   Amphiprion ocellaris (Clown anemonefish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000010792.1, ECO:0000313|Proteomes:UP000257160};
RN   [1] {ECO:0000313|Ensembl:ENSAOCP00000010792.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Exonucleolytic cleavage in the 3'- to 5'-direction to yield
CC         nucleoside 5'-phosphates.; EC=3.1.11.2;
CC         Evidence={ECO:0000256|ARBA:ARBA00000493};
CC   -!- SIMILARITY: Belongs to the DNA repair enzymes AP/ExoA family.
CC       {ECO:0000256|ARBA:ARBA00007092}.
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DR   AlphaFoldDB; A0A3Q1B968; -.
DR   STRING; 80972.ENSAOCP00000010792; -.
DR   Ensembl; ENSAOCT00000017966.1; ENSAOCP00000010792.1; ENSAOCG00000015007.1.
DR   GeneTree; ENSGT00940000176963; -.
DR   Proteomes; UP000257160; Unplaced.
DR   GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   InterPro; IPR004808; AP_endonuc_1.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR   PANTHER; PTHR22748; AP ENDONUCLEASE; 1.
DR   PANTHER; PTHR22748:SF24; ENDO_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF14529; Exo_endo_phos_2; 1.
DR   SUPFAM; SSF56219; DNase I-like; 1.
PE   3: Inferred from homology;
KW   Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022759};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022759};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257160}.
FT   DOMAIN          94..204
FT                   /note="Endonuclease/exonuclease/phosphatase"
FT                   /evidence="ECO:0000259|Pfam:PF14529"
SQ   SEQUENCE   209 AA;  24116 MW;  0EF781030FBFC80E CRC64;
     LCQIAPHTHY TQLDSFYREV MEAWGLARPL VKGLVEKVQK EWKGGIYTSN GTGTARGVAI
     LVPEQLKETV KLIYKEKVGR IIIIDFQHNN ENYRLINIHC PNIEGERKDF VRGLNKWVTN
     KTNCLIVGDF NICLTKLDSA KNNTYKNDTS RTELNKLLER NNLIDIWRNL NPFKLQYSRQ
     QVVEGKLKQT RIDLCLTSPE ITKTVSGVR
//