ID A0A3Q1BAF9_AMPOC Unreviewed; 1482 AA.
AC A0A3Q1BAF9;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Dispatched RND transporter family member 2 {ECO:0000313|Ensembl:ENSAOCP00000011005.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000011005.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000011005.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the dispatched family.
CC {ECO:0000256|ARBA:ARBA00038046}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR STRING; 80972.ENSAOCP00000011005; -.
DR Ensembl; ENSAOCT00000030071.1; ENSAOCP00000011005.1; ENSAOCG00000015271.1.
DR GeneTree; ENSGT00940000159551; -.
DR OMA; MPVTIVW; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035195; P:miRNA-mediated post-transcriptional gene silencing; IEA:Ensembl.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR45951:SF2; PROTEIN DISPATCHED HOMOLOG 2; 1.
DR PANTHER; PTHR45951; PROTEIN DISPATCHED-RELATED; 1.
DR Pfam; PF12349; Sterol-sensing; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 514..531
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 537..555
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 567..593
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 613..633
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 645..667
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 740..758
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1010..1029
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1035..1057
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1064..1088
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1108..1130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 529..667
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 257..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1218..1242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1283..1307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..277
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1289..1307
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1482 AA; 164014 MW; C36D1E8FC21CFEA1 CRC64;
MSLTVYRLNF CTFILKEACR LFHCRLSVNH IFSSLPLCLF FFVFSGIPAV SLCPPDSPAE
AQLTVIQSEG ELCDSCSSLG RPSSSFQLYH QVIGAYDSPQ PRKCPHCSHH GPVKPSVCHN
CHSNATHAEG GVVVKVGHSC NSAHQASRHA AVRCHWLHGS NESRTQKPKQ RHVVTVSFTD
CFCFFYGFLL GSYSQVIVDY PLAALLGCAV LLLGCSLAGF FIGSLPDFSD PLLGFEPRGT
YIGVRQSSLY ELQENTGPGK TLSPLPQQLS KSSGGQDASR VRIKRMPARD SSLDTFLCDA
PDQRLAQLVF RSENSASLWS LKAIHAMCDM EQSRIGSQAQ FQDLCQQHGR VKAKGTSRSD
CCPSWSLGNY LAVLTNASSC LNLTSQQVTE SLNLLRKCAQ YYHEGHLVEA CVERPKHRGC
SSVPSRCKQS RVVFQILHFL VDKDFLGPQT VEYQIPTLKY SLLFLPINKG QHMMEIYMNS
LEGQDLTYNN TTITGIDFGI KQTLFKYYLA RDSVYPILAV VSLLLTMALY LHSLFIVALS
IIAITGSLLT SYFFYKVAFR LSFFPMVNLS AALILLGSCS NQVFLFTDFW NLQLSQNPSA
SLEKRVNRAL QEVGYLILAS GLTSSAAFFS GYLSSITAIR CFSIYLGTAS FISSLLACVW
LPCSFILRER YTKSSSASAA VQGWKPCCSK NTGGFWDTSS RKRCLFSLAQ KLRELKRGLT
DTSNLIFLKI LPCGVVKFRY IWVCWFAVLA AGGTYMACID PGMKLPTLDS RVTQLFRSSH
PFERFDAEYS HMFMFERQRN GEDKPVALML VWGVKPIDNG DHFNPRSNGS LVLDPDFNMS
RPDAQVWLRD LCGRVQNQSF YSPLTPEDKD VITDNICLVE QLVHWVSVRR CSDSDDALHF
CCNDIPFPYP PNVFEKCLSM MLAERYAECH LAHSGGLYFQ PDGRVAALVL AFKTTYLHSF
NFSKTSAFYR EILTWFNREI SGAPQGLEKG WFISQLSLFD LQQSLGSETL VVAGFSVALT
FVLLLVTTWN IPLSIYGTLA VGGSVFVTFG LLVLLEWQLN GIEALFISSA AGLSVDFIAN
YCISYSLAPH SDKIGKVAHT TKRMGCPVAI VSGAFFFMGI ILLPATALLF RKLGIFLFLV
KCVACGFATF FFQSLCCFFG PQRNCGTITL PCCSDQTDAV LSSCAEPGSS SASAANGAFG
RSRARRSYDK EAAGYLYPNH QRQHRQKQPG GGGGGNQGPE QYELQPLGYR LSDSFENSTC
TSKLSNRPSV LSDEIEYCGK DEGRNSMDGE SENTCSHQHK IGQPPPALQT SSPYKDNTLH
PMGLAQADVA KDKLLCKTCR GHTAELKHWS NTSFSSSSSI EETIISHTLE TTDQPSLCKG
PSSSQSHSSC EGLEDSCETC LSDIEPGPSN LQQHEGQEEV HLQPGHLNGK RDTLRLSLKE
TVYDNCGKNR TSQSEEVVIL PNSKPDLPDV WIKRDGQRED TC
//
