ID A0A3Q1BBR8_AMPOC Unreviewed; 4516 AA.
AC A0A3Q1BBR8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Plectin-like {ECO:0000313|Ensembl:ENSAOCP00000007381.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000007381.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000007381.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR Ensembl; ENSAOCT00000002934.1; ENSAOCP00000007381.1; ENSAOCG00000011130.1.
DR GeneTree; ENSGT00940000162855; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR CDD; cd21188; CH_PLEC-like_rpt1; 1.
DR CDD; cd00176; SPEC; 2.
DR Gene3D; 1.20.58.1060; -; 1.
DR Gene3D; 1.20.58.60; -; 5.
DR Gene3D; 3.30.160.780; -; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 3.90.1290.10; Plakin repeat; 6.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR041615; Desmoplakin_SH3.
DR InterPro; IPR041573; Desmoplakin_Spectrin-like.
DR InterPro; IPR049538; PCN-like_spectrin-like_rpt.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR035915; Plakin_repeat_sf.
DR InterPro; IPR001101; Plectin_repeat.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR PANTHER; PTHR23169:SF20; PLECTIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF00681; Plectin; 15.
DR Pfam; PF17902; SH3_10; 1.
DR Pfam; PF18373; Spectrin_2; 1.
DR Pfam; PF21020; Spectrin_4; 1.
DR Pfam; PF21097; SR_plectin_7; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM00250; PLEC; 33.
DR SMART; SM00150; SPEC; 4.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF75399; Plakin repeat; 7.
DR SUPFAM; SSF46966; Spectrin repeat; 4.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 35..143
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 160..265
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 805..862
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1471..1535
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1599..1710
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1998..2031
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2083..2155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2457..2478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2511..2576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4457..4516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 12..39
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1242..1293
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1473..1535
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1613..1703
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2083..2112
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2121..2147
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2457..2477
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4516 AA; 517059 MW; 41FBBC1B10DF2297 CRC64;
MAMYEPAYLP PNAEEQDFIQ AYENVREKYK DERDRVQKKT FTKWVNKHLI KHWKGESQRR
VSDLYEDLRD GHNLISLLEV LSGESLPREK GRMRFHKLQN VQIALDFLRH RQVKLVNIRN
DDIADGNPKL TLGLIWTIIL HFQVSSSISD IQINGQSEDM TAKEKLLLWS QRMTDGYQGI
RCDNFTTSWR DGKLFNAVIH KHYPRLIDMG KVYRQTNMEN LEHAFSVAER DLGVTRLLDP
EDVDVPHPDE KSIITYVSSL YDVMPRVEAT VRSNDLELRW QEYYELVTVL LQWMRHHVMI
FEERKFPASY EEIELLLRQF SKFKETELPV KEQDKNHSKH IYQSFESAVH AGQVKVPPGY
HPIDVEKEWG RLHVAILERE KLLRIEFERL ERLQRIYSKV NMESGMCDDQ LSYLTSLVQS
DIRLLSAGKP AQHTAEVERE LDKAENMIRL LFNDVQMLKD GRHPQADQMY RRVYCLHERL
VNLRSDYNLR PKTASMTTSQ VNLTKSTQQS IMKVRPELDD VTLRYVQDLL AWVEENQRRI
DDAEWGSDLP SVESQLGSHR GLHQTVEDFK SKIERARADE NQLSPVSKGT YREYLGKLDL
QYGKLQNSSK SRLRNLDSLH SFVSAATKEL MWLHDKEEEE VNFDWSDRNS NMTAKKDNYS
GLMRELELRE KKVNDIQAMG DKLVKDGHPG KKTVESFTAA LQTEWSWILQ LCCCIEAHLK
ENTAYYQFFG DVKEAQDKMK KMQENMKKKY SCDRSTTATR LEDLLQDAVE EKEQLNEFKT
LVTGLNKRAR SIIQLKPRNP TTSIKGKTPI QAVCDFKQQE ITVHKGDECA LLNNSQPFKW
KVLNRAGHEA VVPSVCFMVP PVNKEAVDSV SSLDAGHQQM VSMWQKLHID MKSLLSWQYL
MRDYTQIRSW NISMLKTMKP EEYRLIMRNL ELHYQDYMRD SQDSQLFGPD DRMQIEEDYT
KSTQHFDNLL RSMEKGQQNE SLCKNYISEI KDLRLRIEDC EAQTVARIRK PVEKEPLKEC
VQKTTEQKKV QVQLDGLKKD LDKVSVRTNE VLASPQQSAS APVLRSELDV TVQKMDHAHM
LSSVYLDKLK TVEMVIRNTQ GAEGVLKQYE DCLREVHTVP GDIKEVETYR TKLKKMRAEA
EGEQPVFDSL EEELKKASAV SDKMSRVHSE RDVELDHYRQ LLSSLQDRWK AVFTQIDLRQ
RELEQLGRQL GYYRDSYDWL IRWIADAKQR QEKIQAVPIT DSKTMKEQLA QEKKLLEEIE
QNKDKVDECQ KYAKAYIDTI KDYELQLVAY KAQVEPLASP LKKTKLDSAS DNIIQEYVTL
RTRYSELMTL TSQYIKFITD TQRRLEDEEK AAEKIKAEEQ KKMAEMQAEL DKQKQLAEAQ
AKAIAKAQKE AQELKHKMQE EVIRRENAAV DAEKQKKNIQ LELHELKNLS DQQIKDKSQQ
VDEALQSRVK IEEEIRLIRI QLETTVKQKS TAETELKQLR DKANEAEKLR KAAQDEAEKL
RKQVNEETQK KRMAEDELKR KSEAEKEAAK QKQKALEDLE NLRRQAEEAE KQVKKAEVEK
ETQIKIAHEA AQKSAAAELQ SKHISFVEKT SKLEESLKQE HGAVVQLQQE ASRLKKQQED
AEKAREEAEK ELDKWRQKAN EALRLRLQAE EEAHQKSLAQ EEAEKQKEEA EREAKKRAKA
EDSALKQKEM AEKELERQRK VAESTAQQKL TAEQELIRLR ADFDNAEQQR SLLEDELYRL
KNEVAAAQQQ RKQLEDELAK VRSEMEVLSS MKSRLEEETM SNTEKSKQLL EAEAAKMRDL
SDEASKLRAI AEEAKHQRQV AEEEAARQRA EAERILKEKL AAISEATRLK TEAEIALKEK
EAENERLRRQ AEDEAYQRKA LEDQANQHKQ DIEEKIVLLK KSSEAEMERQ KAIVDDTLKQ
RRVVEEEIRI LKLNFEKASS GKLDLELELN KLKNIAEETQ QSKLRAEEEA EKLRKLALEE
EKRRREAEEK VKKIAAAEEE AARQRKAAQD ELERLKKKAE EAKKQKDEAD IEAEKQIVVA
QQAALKCSAA EQQVQSVLAQ QKEDSIMQKK LKEEYEKAKK LAKEAEAAKE KAEREAALLR
QQAEEAERQK SAAEQEAANQ TKAQEDAERL RKEAEIEAEK RKQAEAAALK QKQQADAEMV
KHKKLAEQTL KQKSQVELEL TKVKLKLDET DKQKSLLDDE LQRLKDEVDD AVKQRAQVEE
ELFKVKVQME ELLKLKIRIE EENQRLIKKD KDNVQKFLAE EAENMKKLSQ DAARLSVEAQ
EAARLRQIAE DDLNQQRALA DKMLKEKMQA IQEASRLRAE AELLQRQKDL AQEQAQKLLQ
DKQLMQQRLE EETEEYQKSL EAERKRQLEI TAEAEKLKLQ VYQLSEAQAK AEEEAKKFKK
QADTIAARLH ETEIATKEKM TVVGKLEVQR LHTSKEADDL RKSIADLENE KARLKKEAEE
LQNKSKEMAD AQQKQMEHEK TVLQQTFLTE KEMLLKKEKL IEDEKKRLES QFEEELKKAK
ALKDEQERQR QQMEEEKKKL QATMDAALSK QKEAEKEMQN KQKEMQELEK KRKEQEKILA
EENQKLREKL QQLEKAQKDQ PKKEIDIQTD KEGIINGRSA VELDGVGKKP DPMAFDGIRD
KVPASRLFDL GLLPKKEFDK LKNGKTTVQE LGETENLKHI LKGKNPIAGV LTPSNQKMSI
YQASKEKKIT PGTAMVLLEA QAATGYILDP IKNQKLSVNE AVKKEVIGPE LHNKMLSAER
AVVGYKDPYS GGKISVFEAM KKGLVEHDQA IRVLEAQVAT GGIIDPINSH RVSNATAYKQ
GQYDAEMNKM MEKPSDDTKG YFDPSTQEPL TYSELMTRCT TDPETGLLLL PITDKAAQCS
SMYTEEETKD VFSKTTVSVP FGRFKGKTVT IWEIINSEYF TEDQKKDLLR QYKTGKITIE
KIIKIVITVA EEKEKKNEIT FDGLRAPVPA TELVESKIID KDLYNKLQKG NKTVKEVSEM
EPVHKALKGT NCIAGVVIDS SKATMSFYQA LKKDMMRAGP ALHMLEAQAG TGYVVDPVDN
KKYTVDEAVK AGVVGPELHE KLLSAERAVT GYKDPYTGKT VSLFQAMRKD LIPKEQGIRL
LDAQMTTGGI IDPVKSHRIP HDVACKRNYF DDEMKQTLSS PTDETKCFFD PNTKENVTYA
QLFKTCVTDK KTGLQLLPLS DEAINAKEEP TYSEAQTKEA MTQATVELDS GPFKGRKMTL
WDIINSEYLT EEERLDLLRQ FRSGKFTIEK IIKIIITVVN EKEAKKQEKS TFKGLRAPVP
ASSLCDSKII DKETFDLLQQ GKITPKQVSE NPSVNKYLQG SDSIAGIYLE PTKEKISIYQ
AMKKKLLRHN TGLSLLEAQA GSGFIVDPVR NKYLSVDEAV KSGLVGPELH EKLLSAEKAV
TGYKDPFTGN KISLFEAMQK DLILKEHAMP LLEAQMVSGG IIDAVNSHRV PTDVAYQKKI
FSKEIAKTLS EPSDDNKAFT DPETDENVTY RQLKDKCQRD KDTGLCMLPL SKPQSPTVVE
KTYLYTEEQT QSELTDTKID IPVEGLADKP MNLWDVMNSN LLPEQERQKL MDEYRSGQIT
KERMIIIIIE IMEQREIIRT DSPLSYKTIR RRITIEELYN ARIIDLETYN LLKQGKRDIR
DIMEMTSVKQ YLYGTGCVAG VTTDSSSKIS IYQAMKRGFI QPEIGLSLLE AQAATGFIVD
PVKNETLTVD EAVRKGVVGP EIHDKLLSAE RAVTGYKDPY SGKVISLFQA MKKDLVPEDY
ALKMIEAQTA TGGIIDPEFQ FHLPADVAMQ RGYINKETNE RLNDDVKGFT DPVTNEKVSY
AELLKRCKLD GGLRLLSLGD KRLTFKGLRK QITMEELLRS QIIDQQTVTE LNEGLISVEE
VSNRLSRYLE GTGCIAGVFL EPSKERLSIY QAMKKNMIRP GTAFELLEAQ AATGYVIDPI
KNLKLTVNEA VKMGIVGPEF KDKLLSAERA VTGYRDPYSG RTISLFQAMK KGLILKDHGI
RLLEAQIATG GIIDPEESHR VPVEVAYKRG FFDEEMNEIL TDPSDDTKGF FDPNTEENLT
YLQLMERCIT DPDTGLVLLL LKEKKRERKT SSKSSVRKRR IVIVDPETGK EMTVYEAYRK
GLIDHQTYLE LAEQECEWEE ITMTSSDGTV KSIIIDRRSG RQYDVDDALS RGLIDQNALD
TYRAGNLSIT EFADMLSGNM GGFRSRSSSF GSTTGSTYSS PMSPIPSMKA PAVIWNDPTE
ETGPIAGILD TDTLEKISIT EAIHRNVVDN ITGQRLLEAQ ACTGGIIDPS SGERLSVADA
TEKGLVDKVM VDRLNLAQKA YNGFEDPRTK ERMSASQALK KGWLYYEAGQ RFLEVQYLTG
GLIEPSVEGR VSLDESIRKG TIDARTAQKL RDVSTYSKYL TCPKTKLKIS FKDAMDKSMV
EEGSSLRLLE ASSQSSKGLY SPYNASGPGS AYGSRTGSRT GSRTGSRRGS FDAGSGFSMN
FASSSFTSSS SYSRRF
//
