ID   A0A3Q1BI46_AMPOC        Unreviewed;       849 AA.
AC   A0A3Q1BI46;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Extracellular calcium-sensing receptor-like {ECO:0000313|Ensembl:ENSAOCP00000014102.1};
OS   Amphiprion ocellaris (Clown anemonefish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000014102.1, ECO:0000313|Proteomes:UP000257160};
RN   [1] {ECO:0000313|Ensembl:ENSAOCP00000014102.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3Q1BI46; -.
DR   STRING; 80972.ENSAOCP00000014102; -.
DR   Ensembl; ENSAOCT00000022348.1; ENSAOCP00000014102.1; ENSAOCG00000018845.1.
DR   GeneTree; ENSGT01050000244874; -.
DR   Proteomes; UP000257160; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   CDD; cd15283; 7tmC_V2R_pheromone; 1.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR000337; GPCR_3.
DR   InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR   InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR   InterPro; IPR017978; GPCR_3_C.
DR   InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR   InterPro; IPR017979; GPCR_3_CS.
DR   InterPro; IPR004073; GPCR_3_vmron_rcpt_2.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR24061:SF528; C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED; 1.
DR   PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   Pfam; PF07562; NCD3G; 1.
DR   PRINTS; PR00248; GPCRMGR.
DR   PRINTS; PR01535; VOMERONASL2R.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..849
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018653535"
FT   TRANSMEM        581..602
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        614..636
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        648..672
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        692..711
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        739..760
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        772..792
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        804..828
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          578..842
FT                   /note="G-protein coupled receptors family 3 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50259"
SQ   SEQUENCE   849 AA;  94795 MW;  22A25DFCABDCE92C CRC64;
     MYKMPPVITG LIFIGLLLTS ETVEDEEAPL CHILKSPEFP LMSKEGDVTI GGAFSIHSKI
     TQPPLLFTEK PTRLRCSSVN LREFRFAQTM IFAIEEINRN TFLLPNISVG YRIYDNCGST
     LSSMRAVMAL MNGDEWTLER KCSGQSAVHA IIGESESSST IVLSRTTGPF KMPVISHSAT
     CECLSSRKEY PSFFRTIASD LHQSRALAQL VKHFGWTWVG AVNSDSDYGN NGMAIFLAAA
     QEEGVCVEYT EKFHRSEPEK LLKVVEVIRK STARVIVGFL AHVEMNDLLE QLRLNNITGR
     QFIGVEAWIT ADSLVTPTSF SVLGGSLGFA VQKANISGLQ DFLVKDFWET EFKCEEINRD
     SVTKTASCKE NQDLMELRYN DDDVAELRYS SNIYKAIYAV AYSLHSILKC SHTQGCDKTV
     KVTPWQVVES LKQVNFTVKN GDKVWFDSTG AAVARYEVVN WQRGSDGSIQ FKPVGYYDAS
     LPSGQRFVLN TEAIMWPGGS KELPVSVCSA SCRAGTHKVL QKAKPVCCYD CIPCADGKIS
     NTTDSIDCKK CPEEYWSNQN RDACVLKKVE FLSFTEVMGK ILVFFTLLGV LLTLIVAALF
     LIHKETPLVK ANNSELSFLL LFSLTLCFLC SLTFIGRPSE WSCMLRHTAF GITFVLCISC
     ILGKTIVVLM AFKATLPGRN VMKWFGPTQQ RLSVLAFTLL QVIICILWLT IDPPFPFKNM
     NHYKEKIILE CALGSPVGFW AVLGYIGVLA LLCFIIAFLA RKLPDNFNEA KFITFSMLIF
     CAVWITFIPA YVSSPGKFTV AVEIFAILAS SYGLLFCIFL PKCFIILFRP ETNTKKHIMG
     KTSNSNVHY
//