ID A0A3Q1BL61_AMPOC Unreviewed; 418 AA.
AC A0A3Q1BL61;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Potassium channel subfamily K member 2-like {ECO:0000313|Ensembl:ENSAOCP00000015010.1};
GN Name=KCNK2 {ECO:0000313|Ensembl:ENSAOCP00000015010.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000015010.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000015010.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666,
CC ECO:0000256|RuleBase:RU003857}.
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DR AlphaFoldDB; A0A3Q1BL61; -.
DR STRING; 80972.ENSAOCP00000015010; -.
DR Ensembl; ENSAOCT00000023516.1; ENSAOCP00000015010.1; ENSAOCG00000019738.1.
DR GeneTree; ENSGT00940000156560; -.
DR OMA; IEYMDYY; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR003976; 2pore_dom_K_chnl_TREK.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003:SF21; POTASSIUM CHANNEL SUBFAMILY K MEMBER 2; 1.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01333; 2POREKCHANEL.
DR PRINTS; PR01499; TREKCHANNEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU003857};
KW Ion transport {ECO:0000256|RuleBase:RU003857};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003857};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857}.
FT TRANSMEM 49..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 124..180
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 219..297
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 418 AA; 46379 MW; 58764E8F35F5C6DD CRC64;
VAAPDLLDPK SATHNTKPRL SFSTKPITLT PREESEVVAT VMKWKTVTAI FLLVVLYLVM
GAAVFRSLEQ PHESAQRLAI LSQKLEFLSR HSCVNQSQLE ELVKQVVSAI RSGVNPAGTL
TNHSSLWDLS SAFFFAGTVI TTIGFGNTSP HTEGGRIFCI VYALLGIPLF GFLLAGVGDQ
LGTIFGKGIA KVEKMFVHWD ISQTKIRVIS TLLFVLFGCL LFVALPAAIF KHIEGWSALE
SLYFVVITLT TIGFGDFVAG GSEIEYLDYY KPVVWFWILV GLAYFAAILS MIGDWLRVIS
KRTKEEVGEI RAHAAEWTAN VSAEFKETRR RVSVEIYDKF QRAASIKRKL SSELGFSPAP
ELTLPRRTVS VNFNDERDKI ERDAGLQGLT TPLTRNSGLY MNGLDLERGD ISIIEHLK
//
