ID A0A3Q1BPT5_AMPOC Unreviewed; 1987 AA.
AC A0A3Q1BPT5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Disks large homolog 5-like {ECO:0000313|Ensembl:ENSAOCP00000014874.1};
GN Name=DLG5 {ECO:0000313|Ensembl:ENSAOCP00000014874.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000014874.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000014874.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 80972.ENSAOCP00000014874; -.
DR Ensembl; ENSAOCT00000031629.1; ENSAOCP00000014874.1; ENSAOCG00000019649.1.
DR GeneTree; ENSGT00940000155303; -.
DR OMA; QEHYMAD; -.
DR OrthoDB; 2877432at2759; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR CDD; cd01671; CARD; 1.
DR CDD; cd00992; PDZ_signaling; 4.
DR CDD; cd11860; SH3_DLG5; 1.
DR Gene3D; 2.30.42.10; -; 4.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR001315; CARD.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR006907; DLG5_N.
DR InterPro; IPR035537; DLG5_SH3.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR46360; DISKS LARGE HOMOLOG 5; 1.
DR PANTHER; PTHR46360:SF1; DISKS LARGE HOMOLOG 5; 1.
DR Pfam; PF00619; CARD; 1.
DR Pfam; PF16610; dbPDZ_assoc; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF00595; PDZ; 4.
DR Pfam; PF04822; Takusan; 1.
DR SMART; SM00072; GuKc; 1.
DR SMART; SM00228; PDZ; 4.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 4.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50209; CARD; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR PROSITE; PS50106; PDZ; 4.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..92
FT /note="CARD"
FT /evidence="ECO:0000259|PROSITE:PS50209"
FT DOMAIN 696..785
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 780..871
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1410..1489
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1570..1650
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1661..1729
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1843..1973
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
FT REGION 103..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 930..971
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1064..1166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1264..1409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1494..1561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 188..257
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 306..409
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 438..675
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 103..136
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..969
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1064..1087
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1096..1125
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1146..1166
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1264..1287
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1298..1328
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1343..1390
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1987 AA; 223666 MW; 491C53BABC85AC2C CRC64;
MEPKHKELLE KCYQNLVESI TDADRVVDVL AHCGTLSQSE RYELGHNCSS NSEKVDLLLK
ILTSKDRDHF AEFCSALEAT HPHLHSVLLN GIGPVDHTTG STYSVLSTMP SDSESSSSLS
SLGTPGQASS PPPAHMESHQ VNEKMETVLF QLRHVTRERD DLRKRLALSS PGTTFDDCRP
NSKAGHDYER LKLQCMKAMA DLQSLQNQHS TTLKRCEEAV KKADFYHTLH SRLASEHTQL
KEELEAVRQD NIQLVREHNH VKQACEELRR LHDDDQREVA DMRMLHQQVM REGSSDVLNK
LYDTAVDKLE AMKSDYEALR KHYNEKTANH NADLSRLDQA EEENHRLQKQ LDMLLKQRDA
AIHYQQQYSS SIRRFDNTQQ ELSKATAQNK ELQREMDRLQ SETTRLKTQQ LKAAKDSEKY
KEERDSVISE YRLIMSERDQ VIKEVDRLQT GLEVAEAKLK NTSSERRVAN EELEALRQEL
ASALVDRDRA VCEKNELLEK YCHEVKDKTE AQKELNQACK DIETVREERD VARKERTEAI
IQRDQLLREY YQARQKQDCA TLDMERANKE IEMLRKQYEA ISQELKEALQ EAEVAKCRRD
WAFQERDKIV AERESIRTLC DNLRRERDRA VSDLADALRN LDDMRKQKND ASRELKELKE
KLEDQLEKEA RYRQLMAHSS HDSAIDTDSM EWETEVVELE KHRDMDLKAL GFDIAEGVND
PYLPGDCGIF VTKVDKGSIA EGRLRVNDWL LKINDVDLTN KDRTQVIKTV LSGEGVINMV
VRRRKSLGGR IITPIQINLA GQKDSGIGLE SGVFVATLAA GSPAARDCNL TVGDRLLAIN
GIALENKSLS ECESLLRNCH SSLSISLMKF LPQSSSGQSL FETLRDSEKT SRVQTCEVHT
RNCRNSKHNC STQTDICSCD LGSREEDTCK DTGDSLDSSS SSAHSHHKPF SNSSLHSHSL
STSHSSSEPH PEFCYRRQDL HHRPFTFTPV ISDCTSPQAA VDQLQSSPVK ASGGTWPRVI
AGASIPECTQ LSIYKKPKQR KSIFDVNAFR RPETTPKLDY MSLSQLPKHS PQSSLSESAQ
TPPTPPARSD SFRFKHRQQN SSASDSTITT GTPPASPAQA TSRQDDGEVG KQHYYTDAPP
GETKTNSKKP AEEEGSRHRT EVLEKKRYRP KSAPALRRNV TPLHIPVPMQ VQSFSNDEHS
PEPMDLLRFS PMRTNRYSMQ FAPPSYSSIT AHPAQRGLAP CPAVTAVMRN PVYTAWSHEI
QTNNCPPAPS SGIHPHSHTS PQHQGRLSLD LSHKRTGDMT ETSCSQPPHS THSLPSSARL
SSSATLQFRA ERIKIPPTRY PRSTGSDRGS LSHSECSSPT PPMSPVNLET SSFTSSQSQS
SISTQPRISV SPAPVGDRRK DGPYLEEPRN VTVQKGAEPL GISIVSGENG GVFVSKVTAG
SIAHQARLEY GDQLLEFNGI NLRNANEQQA RLVIGQQCDT VTILAQYNPH MFQLGNHSRS
GSRMESISNQ PTPRESGATT PDHHSNVDTL SEQDEGTMTP PSKQTTPATS PHSSFRLPGS
FTNRSAESRL VRLKRIHVEL GVQICGGNLY GIFVESLDDD SPAKSADGLL TGDLILEYNG
ISMKNKTKED AYLELLKPAE TITFKVQNRV DILAEIKESP GDGFFIRALY EKVAEVEQDL
SFKKDDILYV EDTLPNGNFG YWMAWQLDEN AQKLEKGQIP SKYMMDQEFY RRHSMADMKD
DNGTSKTLSA AARRSFFRRR LKHKRSGSKD GKDLTALDAI STDSLPITED GVSLMYQRVQ
KVECSSPRPV LVLGPLVEAS KDMLVKEAPA KFCRCLPEIM KASQQAIERG VKDCVFIDYK
RRSGHFDVTT VASIKEITEK DCHCLLDIAP HAIERLHSVH IYPIVIFIRY KNAKQIKEQK
DPLYLRDKLS QKHSKEQFEA AQKVEQEYSR FFTGVVQGGS VSYICTQIMT IVEQEQSKVL
WIPDGAP
//
