ID A0A3Q1BQX1_AMPOC Unreviewed; 580 AA.
AC A0A3Q1BQX1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Dystrobrevin {ECO:0000256|PIRNR:PIRNR038204};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000017002.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000017002.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|PIRNR:PIRNR038204}.
CC -!- SIMILARITY: Belongs to the dystrophin family. Dystrobrevin subfamily.
CC {ECO:0000256|ARBA:ARBA00009563, ECO:0000256|PIRNR:PIRNR038204}.
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DR AlphaFoldDB; A0A3Q1BQX1; -.
DR Ensembl; ENSAOCT00000026147.1; ENSAOCP00000017002.1; ENSAOCG00000022134.1.
DR GeneTree; ENSGT00940000153897; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd16244; EFh_DTN; 1.
DR CDD; cd02334; ZZ_dystrophin; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR017432; Distrobrevin.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR015153; EF-hand_dom_typ1.
DR InterPro; IPR015154; EF-hand_dom_typ2.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR12268:SF22; DYSTROBREVIN BETA; 1.
DR PANTHER; PTHR12268; E3 UBIQUITIN-PROTEIN LIGASE KCMF1; 1.
DR Pfam; PF09068; EF-hand_2; 1.
DR Pfam; PF09069; EF-hand_3; 1.
DR Pfam; PF00569; ZZ; 1.
DR PIRSF; PIRSF038204; Distrobrevin; 1.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF47473; EF-hand; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS01357; ZF_ZZ_1; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|PIRNR:PIRNR038204};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT DOMAIN 211..267
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT REGION 481..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 555..580
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 393..469
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 483..502
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..580
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 580 AA; 64274 MW; A3F772738BDB4802 CRC64;
MEEGGQRDRG RRIQTMAGAE GRQIFVELVH LLDIYHVIEA VRDAGLNAVE LNAGISVIRL
ENLVSSLFNQ LSKRLPTTHT INPQESTVLL VEFILAAVDG RLTVLSVKAM LATLCGGKLV
DKLRYVFSQV SDSSGVLVQS KFDSFLREAL KLPTAVHEGP SFGYTHTSAR SCFPQHKRVM
LNMFLDIVAD PPQCLVWLPL MHRLANVENV YHPVSCSYCR GNGMTGFRYR CLRCRGYQLC
QNCFWRGNAS GSHSNQHQMK EHSSWKSPAT KFGRALSRTL GCVSSREAPH PIYPEEPERT
LNLSNIVPSR PIGSPSEAML LSSPPPDLSA AQRMNEEHAL IAAYVNRLQS SPRGVDSPSR
QDEEHKLIAR YTSRLAETDG AGVSKISINF DVNKQKRELI AQLECKNREI LAEIKRLRAE
HDAACQPSPE KGTTNPTLLA ELRLLRQRKD ELEQRMSSLQ ESRRELMVQL EGLMKLLKAQ
AAGSSHASPS RPSPSTVRSV GAASPQAHMY PPQDSLAGVG GDVQEAFAQG PRRNLRNDLL
VAADSITNTV SSLVKELHSD DGREEEERLL NGKDRGKLIS
//
