ID A0A3Q1BRK3_AMPOC Unreviewed; 686 AA.
AC A0A3Q1BRK3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Cleavage and polyadenylation specificity factor subunit 3-like {ECO:0000313|Ensembl:ENSAOCP00000016990.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000016990.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000016990.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A3Q1BRK3; -.
DR STRING; 80972.ENSAOCP00000016990; -.
DR Ensembl; ENSAOCT00000026138.1; ENSAOCP00000016990.1; ENSAOCG00000022056.1.
DR GeneTree; ENSGT00940000155699; -.
DR OrthoDB; 169081at2759; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR CDD; cd16292; CPSF3-like_MBL-fold; 1.
DR Gene3D; 3.40.50.10890; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR022712; Beta_Casp.
DR InterPro; IPR021718; CPSF73-100_C.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR011108; RMMBL.
DR PANTHER; PTHR11203; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11203:SF11; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3; 1.
DR Pfam; PF10996; Beta-Casp; 1.
DR Pfam; PF11718; CPSF73-100_C; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR Pfam; PF07521; RMMBL; 1.
DR SMART; SM01027; Beta-Casp; 1.
DR SMART; SM01098; CPSF73-100_C; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160}.
FT DOMAIN 31..217
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT DOMAIN 253..374
FT /note="Beta-Casp"
FT /evidence="ECO:0000259|SMART:SM01027"
FT DOMAIN 484..685
FT /note="Pre-mRNA 3'-end-processing endonuclease
FT polyadenylation factor C-term"
FT /evidence="ECO:0000259|SMART:SM01098"
SQ SEQUENCE 686 AA; 77377 MW; 983BF8BEF346E774 CRC64;
MAAKRKADVT VPAEESDQLL IRPLGAGQEV GRSCIILEFK GRKIMLDCGI HPGLEGMDAL
PYIDLIDPAE IDLLLISHFH LDHCGALPWF LQKTSFKGRT FMTHATKAIY RWLLSDYVKV
SNISADDMLY TETDLEDSME KIETINFHEV KEVAGIKFWC YHAGHVLGAA MFMIEIAGVK
LLYTGDFSRQ EDRHLMAAEI PSVKPDILIT ESTYGTHIHE KREEREARFC NTVHDIVNRE
GRCLIPVFAL GRAQELLLIL DEYWQNHPEL HDIPIYYASS LARKCMAVYQ TYINAMNDKI
RKAININNPF VFKHISNLKS MDHFDDIGPS VVMASPGMMQ SGLSRELFES WCTDKRNGVI
IAGYCVEGTL AKHIMTEPDE ITTMSGQKLP LKMSVDYISF SAHTDYQQTS EFIRALKPPH
VILVHGEQNE MARLKAALIR EYEDNDEVHI EVHNPKNTEA VTLNFRGEKL AKVMGLLADQ
KCAQGQRVSG ILVKRNFNYH ILTPSDLSDY TDLSMGTVTQ SQAIPYTGPI SLLVSQLRSL
AGDVEQVERA EKITVRIFKS ITLVHEAGMV LLEWIANPLN DMYADAVATV VLEVQSNPNA
QKFLEGKKET FDMELFVERL ELMLHDMFGD DCVNFKDRKN LNVTVGGATA SVDPETRSVV
CAEDESLREM VEVAVHRLYD ALSPAF
//
