ID A0A3Q1C1S8_AMPOC Unreviewed; 430 AA.
AC A0A3Q1C1S8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=T-box transcription factor T {ECO:0000256|ARBA:ARBA00040703};
DE AltName: Full=Brachyury protein {ECO:0000256|ARBA:ARBA00041469};
DE AltName: Full=Protein T {ECO:0000256|ARBA:ARBA00042501};
GN Name=TBXT {ECO:0000313|Ensembl:ENSAOCP00000019883.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000019883.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000019883.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3Q1C1S8; -.
DR Ensembl; ENSAOCT00000014456.1; ENSAOCP00000019883.1; ENSAOCG00000003668.1.
DR GeneTree; ENSGT00940000157912; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0009790; P:embryo development; IEA:UniProt.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20192; T-box_TBXT_TBX19-like; 1.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR002070; TF_Brachyury.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR PANTHER; PTHR11267:SF83; T-BOX TRANSCRIPTION FACTOR T; 1.
DR Pfam; PF00907; T-box; 1.
DR PRINTS; PR00938; BRACHYURY.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 39..212
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT REGION 410..430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 430 AA; 47414 MW; C0FA1D35BEEA5941 CRC64;
TTEGNTRYRV DHLLSAVESE LQAGSEKGDP TERELKVSLD ENELWQKFKD LTNEMIVTKN
GRRMFPVLKV NVSGLDPNAM YSFLLDFASA DNHRWKYVNG EWVPGGKPEP QTPSCVYIHP
DSPNFGAHWM KAPVSFSKVK LTNKLNGGGQ IMLNSLHKYE PRIHIVRVGG PRRMITSHSF
PETQFIAVTA YQNEEITSLK IKYNPFAKAF LDAKERSDNK DLREDASENQ QSGYSQLGSW
FIPGTGSLCP PASPHSQFGS PISLSPSHGC ERYSTLRNHR SVPYASPYGH RTNSPTSYID
NSSPCLSMLS SHDNWSSLQM PAHSSMMPMA HNSTSGTNSS QYTSLWSVSN SPLTPVSQNG
GINNCLSSQF LRGSGSHYPS LSHSVTVPSS GSPMYDSSTA TEVHDTTAQY DVSPHGRLPS
AWTPVTPPSL
//
