ID A0A3Q1C631_AMPOC Unreviewed; 858 AA.
AC A0A3Q1C631;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Cyclic nucleotide gated channel subunit beta 1a {ECO:0000313|Ensembl:ENSAOCP00000022857.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000022857.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000022857.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A3Q1C631; -.
DR STRING; 80972.ENSAOCP00000022857; -.
DR Ensembl; ENSAOCT00000006913.1; ENSAOCP00000022857.1; ENSAOCG00000008808.1.
DR GeneTree; ENSGT00940000162283; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.10.287.630; Helix hairpin bin; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45638:SF16; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL BETA-1; 1.
DR PANTHER; PTHR45638; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS00888; CNMP_BINDING_1; 1.
DR PROSITE; PS00889; CNMP_BINDING_2; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 234..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 435..456
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 760..781
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 801..834
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 542..646
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 25..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 156..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..82
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 858 AA; 97886 MW; 16C0A0B6EF579DE9 CRC64;
RQGSNHVIYL LPSFTRCLLD VCPAEVEEQQ EEPTKAPSPP AEDVTPSSTD VEPASERRDL
DSPTSQPITQ QPEAQPAEAP PTTDQVNIYE TLNTSAGFIP IQTDLYLVPP PSILHVDHRA
VSCRGRPLSA ASVGSVVIQD RLNDLVKLFK GRTERQKDRL VDPDESEEES PSEKKDEAPP
AEKEEEEEEP VFQFELLGHP VKFYAPTNLP PLRSWLRSIL EYRFPSSIDP FTDLIYVLWL
FLVVAAWNWN VWLIPVRWAF PYQTPENIHL WLLADYTCDL IYVLDILVFQ PRLQFVRGGD
IVCDKKDMRE NYMSTERFKM DVISLFPMEI FYYFTGVNSL LRFPRLLKYS AFFEFNDRIE
AVMKKAYIYR VIRTSTYLLY SLHINACLFY WGSDYEGLGS TKWVYNGKGF AYIRCYYFAV
KTLITIGGLP DPTTVFEICF QLINYFVGVF AFSIMIGQMR DVVGAATAGE NYYRACMDST
VKYMNSYKIP KEVQNRIKTW YDYTWKSQGM LDEQELLVQL PAKMRLDIAV DVNYAIVSKV
ALFQGCDRQM VFDMLTRLKS VVYLPGDFVC KKGEIGREMY IIKQGEVQVV GGPDLQTVFV
TIRAGSVFGE ISLLAGGGGN RRTANVKAHG FANLFILDKK DLAEILVHYP ESQKLLRKKA
KTMLTKDKKP DEKEGKEAVE VIPPRPDTPK LFKAALKVTE QAGIEGTFSK LKKAYKSTDS
PTEVRAEIPP AACWGSSELR YCRLGERNDG KNTRRRVSSL SLFILIFFYV LFSAFYLHLY
SFLSFLHLYP GPLPPSLSFP LFLHLCLHPF LSSIFSPSFL SGILVSAPSC PLSLPLRRRP
PWLRSHLRLR CTAALRSL
//
