ID A0A3Q1C6S9_AMPOC Unreviewed; 593 AA.
AC A0A3Q1C6S9;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Rhophilin Rho GTPase binding protein 1 {ECO:0000313|Ensembl:ENSAOCP00000022420.1};
GN Name=RHPN1 {ECO:0000313|Ensembl:ENSAOCP00000022420.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000022420.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000022420.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RHPN family.
CC {ECO:0000256|ARBA:ARBA00010369}.
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DR AlphaFoldDB; A0A3Q1C6S9; -.
DR Ensembl; ENSAOCT00000008013.1; ENSAOCP00000022420.1; ENSAOCG00000008012.1.
DR GeneTree; ENSGT00940000153837; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd11633; HR1_Rhophilin-1; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.25.40.280; alix/aip1 like domains; 1.
DR Gene3D; 1.10.287.160; HR1 repeat; 1.
DR InterPro; IPR004328; BRO1_dom.
DR InterPro; IPR038499; BRO1_sf.
DR InterPro; IPR011072; HR1_rho-bd.
DR InterPro; IPR036274; HR1_rpt_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR047138; RHPN1_2.
DR PANTHER; PTHR23031; RHOPHILIN; 1.
DR PANTHER; PTHR23031:SF6; RHOPHILIN-1; 1.
DR Pfam; PF03097; BRO1; 1.
DR Pfam; PF02185; HR1; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM01041; BRO1; 1.
DR SMART; SM00742; Hr1; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF46585; HR1 repeat; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS51180; BRO1; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS51860; REM_1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01207, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160}.
FT DOMAIN 3..76
FT /note="REM-1"
FT /evidence="ECO:0000259|PROSITE:PS51860"
FT DOMAIN 86..387
FT /note="BRO1"
FT /evidence="ECO:0000259|PROSITE:PS51180"
FT DOMAIN 444..507
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 532..571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 53..80
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 545..559
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 593 AA; 67187 MW; 8158ACE7ECA25C31 CRC64;
GCDPFAQTQR SKLQHRRARI NQQINKEMRM RAGAENLFAT TNNKVRETVA LELSFVNSNL
QLLKEELEEL NSNMEAYQMD EAVNVPMIPL GLKETKEVDF TVSVQDFICE HYGEDSSLYD
KEIKELIELR QQAMRTPSRN QAGLELLMEY YNQLYYLDQR FFPAHRNLGV QFHYDSLTGV
PSCQRALAFE KGSVLFNIGA LYTQIGARQD RSAACGIDRA IDAFQRAAAF NYLKENFSNA
PSLDMSCPSL CMLVRLMVQE CVFERVTLTT QDTHFTSQLC LAQEAARVSD VYLLVQQTMT
QPLMKDYVPF SWASMVQVKS EHFRALSHYY AAVALCKAHL RRAVIRHEEA MRVHSLCKIL
RKMDILQDVL SLTHKRSLDK YSELDREDDF DETAEAPEIQ HTHWKPDITP PNFSTVQVTD
IFQRLMQGPL SVFCARARWG PVRLICLQRR EGGLGLTLRG DSPVLVAGVV PGGCAEAGLR
EGDYIVAVDG QDCKWAKHGE VVHMLKSCSD RGVEISVVTL HSYDVERRAI VPSHGSDKEN
TRQRLLSGAK GQSSASLLNW NRKKKREGSG VTKRIGSTFS LSFGSIRDTE AMY
//
