ID A0A3Q1C860_AMPOC Unreviewed; 554 AA.
AC A0A3Q1C860;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=T-box transcription factor 6 {ECO:0000313|Ensembl:ENSAOCP00000016386.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000016386.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000016386.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR AlphaFoldDB; A0A3Q1C860; -.
DR STRING; 80972.ENSAOCP00000016386; -.
DR Ensembl; ENSAOCT00000025348.1; ENSAOCP00000016386.1; ENSAOCG00000021325.1.
DR GeneTree; ENSGT00940000160732; -.
DR OMA; PPYRPEM; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0000785; C:chromatin; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0048514; P:blood vessel morphogenesis; IEA:Ensembl.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0048641; P:regulation of skeletal muscle tissue development; IEA:Ensembl.
DR GO; GO:0021523; P:somatic motor neuron differentiation; IEA:Ensembl.
DR GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR PANTHER; PTHR11267:SF104; T-BOX TRANSCRIPTION FACTOR TBX1; 1.
DR Pfam; PF00907; T-box; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..180
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT REGION 178..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 314..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 437..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..212
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 222..252
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 261..281
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..335
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..460
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 554 AA; 59814 MW; D87618BC362E8419 CRC64;
MELENSSLWK QFSSVGTEMI ITKKGRRMFP GLRLKLSGLN PSLRYILLLD IVPLDNSRYR
FQGGGWQAVG SAEARLPDRV FIHPDSPATG AHWQSRTISF HYAKLTNNTL DTQGHIILHS
LHRYQPRVHV IEARDVLRWG GGQHSFVFPE TQFITVTAYQ NNKITELKIN SNPFAKGFRE
DGMNSKNSSS FPSAPLPQPS SSFSSLPSSD TSDPQPSIPP IDYPSLLSSS PTLSAAATTP
SLQQTSFTFP TPPPSNSSSP QPLLPSSSSP SSNPYHAIPE TISPQTDASF AAPSSTCHSG
QMSAQSLLIQ PNQTLQQEPG GNGSPSNQSS AAFIYPNVLP PNPDSAQPLN QPAAPTLPCS
LPAHGASTSF TFPSVPPHVQ NLSFPNVSPS PALHLQNLSH QAQPLTAAFP PSSFAHPSSS
LPHPSFQPSA CLASSFQQSA GTHPQNLPNP SSSSSTPSYP PVEIGAIPQF NPAPPYRPEM
VLHHPSLLPQ LDSSLPSSTP PPSLYPAFPS YPLRLCQDAH SSLSIPFRHL YRQHQHGHPH
PQGSYLDMST RAVF
//
