ID A0A3Q1C8J4_AMPOC Unreviewed; 1712 AA.
AC A0A3Q1C8J4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Kinase D-interacting substrate of 220 kDa-like {ECO:0000313|Ensembl:ENSAOCP00000023842.1};
GN Name=KIDINS220 {ECO:0000313|Ensembl:ENSAOCP00000023842.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000023842.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000023842.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR Ensembl; ENSAOCT00000004386.1; ENSAOCP00000023842.1; ENSAOCG00000010304.1.
DR GeneTree; ENSGT00940000156714; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011646; KAP_P-loop.
DR PANTHER; PTHR24116; KINASE D-INTERACTING SUBSTRATE OF 220 KDA; 1.
DR PANTHER; PTHR24116:SF1; KINASE D-INTERACTING SUBSTRATE OF 220 KDA ISOFORM X1; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 3.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF07693; KAP_NTPase; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 11.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 10.
DR PROSITE; PS50088; ANK_REPEAT; 10.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 505..526
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 533..554
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 667..687
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 694..713
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 45..77
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 78..110
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 111..143
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 144..176
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 177..209
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 210..242
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 243..275
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 276..308
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 342..374
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 375..398
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 448..958
FT /note="KAP NTPase"
FT /evidence="ECO:0000259|Pfam:PF07693"
FT REGION 1154..1176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1268..1302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1320..1355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1403..1559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1603..1671
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1158..1176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1324..1355
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1408..1427
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1446..1462
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1543..1559
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1610..1671
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1712 AA; 189189 MW; 384016AE77F3A730 CRC64;
MDTTTSLKMT SLAVQSLFSY VEEENLAAVK AHLDKFKDVD SRSDNGQTPL MVAAEQGNLE
ILQELIRRGA NVNLDDVDCW TALISAAKEG HIEVVRELLE NNANLEHRDM GGWTALMWAA
YKGRTDVAQL LLEKGANPNI TGQYSVYPII WAAGRGHAEI VHLLLQHGAK VNCSDKYGTT
PLIWAARKGH YESVMHLLAN GADVDQEGAN SMTALIVAVK GGYTEVVKEL LKRNPNVNMT
DKDGNTALAI AAKEGHTEIV QDLLDAGTYV NIPDRSGETM LIGAVRGGHV EIVRALLNKY
ADIDVRGQDA KTALYWAVEK GNATMVRDIL QCNPDTESCT KEGETPLIKA TKMRSIEIVE
LLLDKGAKVS AMDKKGDTPL HIAIRGRSRK LAELLLRNPK DGRLLYRPNK AGETPYNIDC
THQKSILTQI FGAKHLSPSE SDGDMLGYDL YSSALADILS EPTMQPPICV GLYAQWGSGK
SFLLKKLEDE MKTFAGQQIE PLFQFSWLVV FLTLLLCGSV AVVLGFTVDP KLAIAVSLSL
LALLYIFFVL VYFGSRRERE SWNWAWVIST RLARQVGYLE LLLKLMFVNP LELPEQTTRA
LPVRFLFTDY NRLSSVGGET SMAEMIATLS DACEREFGFL ATRLFRVFKN DEVQGQKWKK
TCCVPSFVLF ALTLGCLITG MALLAIFKVD RANLTVNAVL IAMASVVGLA LLLNCRTWWQ
VADSVFKSQR KRLHSAANNL HQLKSEGFMK VLKHEVELMS KMAKTIDGFT QNQTRMAVII
DGLDACEQDK VLQMLDTVRV LFSKGPFISI FASDPHIIIK AINQNLNSVL RDSNINGHDY
MRNIVHLPVF LNSRGLSTAK KLCMATPTNG EAVPADGWHE DMDRRVSQGS LAQDQVKLGG
KSTLSRRDTY RRRQMQRTIT RQMSFDLTKL LVTEDWFCDI SPQTMRRLLN IVSITGRLLR
ANQIIFNWDR LASWINLTEE WPYRTSWIIL FLEEADGVSD QVTLKTIYER ISKNIPTTKD
VEPLLEIDGD IRSFEVFLSS RTPVLTARDV EMFLPCTVNL DPKLREIIAD VRAAREQMHI
GGVTYPTMPL QEAVPRPQSG YGQHSTACSP TGSFAGSLPP QPHSAYFSGM TGPQHPFYNR
PYFPHHVYHL PRHYSHHLPS SSRPSVKPSG QPQDTNGLHL KSVPYKLKQI CPAVLLSSLN
TDAVCERLRQ IDGIDPNMLS QYTSTIKKAN INGRVLTHCN LDELKKEMEM NFGDWQLFRG
MVMEQRHAES QAMLQDESRA ASEQGSSVHH GEPTRRSGGA QHEAATFSLN LSFEELSGVG
LEEPPRRNNN NSHWPVANHR TSSMSSLNSQ ESSNDICKLT DKQQAEYRDA YREYIAQMAQ
LEMSGSGGER PVQPHPGQFL QAASSEDKGA KEGADQDSRK SFTKRGSKSS DATDFASGTD
AQPLDPISEE DEKLDHSSSS RTPGCRKKAA GSYYHKLPND EDSGPEEADT TTPLLHKEAR
ADALSSQGGS QPTGLLTKPG FLTEILLDKK DSSDSGMRSS DSSSDRSLEE AEGDTDRARE
ALKPSLIELE LEGLVKKRGL LPSSLQDAPV ARMSICSEAP SEASLMASSP DEGWPSSGVS
NLNRTVSNTT LNNNTSSPTD TNTNTNNSHQ HQANITGTES TTTSSSSSSS SIISPAVIIT
PGSSTANTTA ATIHHNQNLR TISLGDERES VL
//
