ID A0A3Q1CF56_AMPOC Unreviewed; 1695 AA.
AC A0A3Q1CF56;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Myosin-9 {ECO:0000256|ARBA:ARBA00039816};
DE AltName: Full=Myosin heavy chain 9 {ECO:0000256|ARBA:ARBA00041440};
DE AltName: Full=Myosin heavy chain, non-muscle IIa {ECO:0000256|ARBA:ARBA00042289};
DE AltName: Full=Non-muscle myosin heavy chain IIa {ECO:0000256|ARBA:ARBA00043098};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000024298.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000024298.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, Cortical
CC granule {ECO:0000256|ARBA:ARBA00037865}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR STRING; 80972.ENSAOCP00000024298; -.
DR Ensembl; ENSAOCT00000003120.1; ENSAOCP00000024298.1; ENSAOCG00000011071.1.
DR GeneTree; ENSGT00940000155632; -.
DR OMA; DLCLEDY; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd14932; MYSc_Myh18; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 4.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 4.10.270.10; Myosin, subunit A; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF16; MYOSIN-9; 1.
DR Pfam; PF00612; IQ; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 1.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000257160}.
FT DOMAIN 25..75
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 79..778
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 656..678
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT COILED 842..1683
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 172..179
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1695 AA; 196910 MW; 3B2C8240EE086405 CRC64;
MTDADKFLYG DRGGMNNPLA QADWATKKLV WVPSEKLGFE AGSVKEEQGE ECVVELTDSG
KKVKVNKDDI QKMNPPKFSK VEDMAELTCL NEASVLHNLK ERYYSGLIYT YSGLFCVVIN
PYKYLPIYTE EIVNMYKGKK RHEMPPHIYA ITDTAYRSMM QDREDQSILC TGESGAGKTE
NTKKVIQYLA HVASSFKSKK DQVSAAVGEL EKQLLQANPI LEAFGNAKTV KNDNSSRFGK
FIRINFDVNG YIVGANIETY LLEKSRAIRQ AKDERSFHVF YYMLTGAGDK LRSELCLEDY
SKYRFLSNGN VTIPGQQDKD MFIETMDAFK IMSIPEEERI GLLKVVSAVL QLGNMSFKKE
RHSDQASMPD DTAAQKVCHL LSINVTDFTR AILSPRIKVG RDYVQKAQTQ EQAEFAVEAL
AKASYERMFR WLVLRINKAL DKTKRQGASF IGILDIAGFE IFELNSFEQL CINYTNEKLQ
QLFNHTMFIL EQEEYQREGI EWSFIDFGLD LQPCIDLIEK PAGPPGILAL LDEECWFPKA
TDKSFVEKVV QEQGTHPKFQ KPKKLKDDAD FCIMHYAGKV DYKADEWLLK NMDPLNECVA
TLLNQSTDKF TADLWRDMDR IVGLDKVAGM SDSMHGAFKT RKGMFRTVGQ LYKEQLGNLM
ATLRNTNPNF VRCIIPNHEK KAGKLEPHLV LDQLRCNGVL EGIRICRQGF PNRIVFQEFR
QRYEILTPNA IPKGFMDGKQ ACVLMIKALE LDPNLYRIGQ SKVFFRAGVL AQLEEERDMK
ITDVIISFQA WCRGYVARKA FAKRQQQLTA MKVIQRNCAA YLKLRNWQWW RLFTKVKPLL
QVTRQEEEML AKEEELVKVK ERQLQAEEQL KEYENKQQQL NAEKLALQEQ LQAETELCAE
AEEMRARLAT RKQELEEILH DLESRLEEEE ERVTQMQTDR KKMQQNITEL EQQLDEEEAA
RQKLQMEKVT TDAKLKKQEE EIMVLDDQNN KLNKEKKLLE ERISEFTTNL TEEEEKSKSL
QKLKNKHEAM ITDLEDRLRK EEKIRQELEK NRRKLEGDST ELSDQIADLQ AQIAELRAQL
AKKEEELLAA LAKIEEEAAA KNTAHKKIRE LEAQISELQE DLELERQARS KAEKHRRDLG
EELEALKTEL EDTLDSTAAQ QELRTKRETE VTQLKKTLEE EAKLHEQQMA DMRHKHNQAF
DEINEQLEQA KRNKVSVEKS KQALESEWNE LQIELKTLTQ SKGDSEHRRK KAEAQVQELQ
VKFGESERQR QEFADKITKM QSELDNVNSL LSEAEGKSIK SSKDLSSVES QLQDTQELLQ
EETRQKLSVS TRLRQLEDEQ NRLQEMLEEE EECKKNVEKQ VSSLQAQLAD MKKKLELETS
SLEGAEECRK KIQREMDSVT QQLEEKSAAY DKLDKTKTRL QQELDDLLVD QSQMRQMISN
LEKRQKKFDQ MLAEEKTIST QYAEERDRAE AEAREKETRA LTLARELETM TDMKDELDRA
NKMLKAEMED LVSSKDDVGK SVHELERSKR AMEQQLEEMR VQLEELEDEL QATEDAKLRL
EVNMQAMKAQ FDRDLQARDE QGEERRKQLV RQVREMEVEL EDERRQRSQA LSSRKKLEMD
LLDLEAQIDA ANKGRDEALK QLKKLQALMK EQMRELDELR LARDEAVNLA KESEKKYKTL
EADTLHFQEV RKEAT
//
