ID   A0A3Q1CFB3_AMPOC        Unreviewed;       348 AA.
AC   A0A3Q1CFB3;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Probable flap endonuclease 1 homolog {ECO:0000313|Ensembl:ENSAOCP00000026397.1};
OS   Amphiprion ocellaris (Clown anemonefish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000026397.1, ECO:0000313|Proteomes:UP000257160};
RN   [1] {ECO:0000313|Ensembl:ENSAOCP00000026397.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR   AlphaFoldDB; A0A3Q1CFB3; -.
DR   STRING; 80972.ENSAOCP00000026397; -.
DR   Ensembl; ENSAOCT00000017430.1; ENSAOCP00000026397.1; ENSAOCG00000014628.1.
DR   GeneTree; ENSGT00940000155807; -.
DR   OMA; CRQTRME; -.
DR   OrthoDB; 5479162at2759; -.
DR   Proteomes; UP000257160; Unplaced.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   CDD; cd09907; H3TH_FEN1-Euk; 1.
DR   Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR   InterPro; IPR008918; HhH2.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR006086; XPG-I_dom.
DR   InterPro; IPR006084; XPG/Rad2.
DR   InterPro; IPR006085; XPG_DNA_repair_N.
DR   PANTHER; PTHR11081:SF49; FLAP ENDONUCLEASE 1 HOMOLOG-RELATED; 1.
DR   PANTHER; PTHR11081; FLAP ENDONUCLEASE FAMILY MEMBER; 1.
DR   Pfam; PF00867; XPG_I; 1.
DR   Pfam; PF00752; XPG_N; 1.
DR   PRINTS; PR00853; XPGRADSUPER.
DR   SMART; SM00279; HhH2; 1.
DR   SMART; SM00484; XPGI; 1.
DR   SMART; SM00485; XPGN; 1.
DR   SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
PE   4: Predicted;
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257160}.
FT   DOMAIN          1..95
FT                   /note="XPG N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00485"
FT   DOMAIN          115..185
FT                   /note="XPG-I"
FT                   /evidence="ECO:0000259|SMART:SM00484"
FT   REGION          297..348
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   348 AA;  39549 MW;  80C0D0B8FB36C3CA CRC64;
     MGITKLAELI RSDAPDAVSY KEIGDYTGKV IALDTSIVVN QFRAATPLLS PLTGLFFRTL
     TFLEHDIKPV FVFDGKPPRE KTPALKKRAA AAGWNSFNRT GIASSQTRDC LQLLKHLGVP
     VIQAPGDAEA LCAHLVREGS VDAVASEDMD TLPFGASAVI RQLNAKRDSE VTEYSLPKLL
     EKLQINQEEF VDLCILLGCD YCEKIHGLGP KKALKLIQKH RTIENVVLHI NRETHPVPDL
     WKYKEARKIF LDGPQTPTPE LIWTEPDEEA VVEFLCHTKR VKEERIRNRM KTFRTLRENR
     REERENEKTA GRSKQTCMKD FFRVTRKREQ TMETADSLSV NKKRPKSK
//