ID   A0A3Q1CFN5_AMPOC        Unreviewed;       574 AA.
AC   A0A3Q1CFN5;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Neuralized E3 ubiquitin protein ligase 1B {ECO:0000313|Ensembl:ENSAOCP00000024473.1};
OS   Amphiprion ocellaris (Clown anemonefish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000024473.1, ECO:0000313|Proteomes:UP000257160};
RN   [1] {ECO:0000313|Ensembl:ENSAOCP00000024473.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q1CFN5; -.
DR   Ensembl; ENSAOCT00000002703.1; ENSAOCP00000024473.1; ENSAOCG00000011329.1.
DR   GeneTree; ENSGT00940000157079; -.
DR   Proteomes; UP000257160; Unplaced.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd16786; mRING-HC-C3HC5_NEU1B; 1.
DR   Gene3D; 2.60.120.920; -; 2.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR037962; Neuralized.
DR   InterPro; IPR006573; NHR_dom.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR12429:SF10; E3 UBIQUITIN-PROTEIN LIGASE NEURL1B; 1.
DR   PANTHER; PTHR12429; NEURALIZED; 1.
DR   Pfam; PF07177; Neuralized; 2.
DR   Pfam; PF13920; zf-C3HC4_3; 1.
DR   SMART; SM00588; NEUZ; 2.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS51065; NHR; 2.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          49..205
FT                   /note="NHR"
FT                   /evidence="ECO:0000259|PROSITE:PS51065"
FT   DOMAIN          298..452
FT                   /note="NHR"
FT                   /evidence="ECO:0000259|PROSITE:PS51065"
FT   DOMAIN          522..562
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          452..480
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          490..509
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   574 AA;  62029 MW;  5F60A7C3B561F086 CRC64;
     MGNTTPKPLI DATLQPRPVA SRQYYTLPNN GAGVERRTSA PPVSINVESP RFHPHAKGKN
     IRLDGQLRRA TRKNSFCNGI TFSHRPVHLY EKVRLRLTGV HTGWSGALRF GFTSLDPSEL
     VATDIPKYAC PDLVTRPGYW AKALPERLAL KDNVLSFWAD RHGRVFYSIN EGEPILFHCG
     LSIGCPLWAI IDIYGITQEV TLLDSTFAES VGSSCLSAAR LSAYLPQSSH DSANYSNNQL
     ENNQAAAAKM ANLQLSNYTQ LIPCCSSTSS SATPSSSAST GFSVPRASRG LPSPLDNDLH
     FHPVRGSDVI LSADRSAACI HFLDSSRTLV FSDRPLHIGE TLYVEVGHLG LPYFGALSFG
     LTSCDPASLH AGDLPADPEV LLDRKEYWVV HRGFPMPCSG DVLSFSLLPS GEVHHGVNGA
     GRGRLLCVDS SQVLWAFFTL HGAVNRLRIL GTLQSSPPST SPTTSQSSSP DDSDSDLAFS
     VNRSSSASES SLVTAPSSPL SLPTSPSLTA SELPPAGKNG ECTICFDQEV DTVIYTCGHM
     CLCNDCGLKL KRQINACCPI CRRPIKDVIK TYRP
//