ID   A0A3Q1CI58_AMPOC        Unreviewed;       239 AA.
AC   A0A3Q1CI58;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=rRNA methyltransferase 2, mitochondrial {ECO:0000256|ARBA:ARBA00041184};
GN   Name=MRM2 {ECO:0000313|Ensembl:ENSAOCP00000025239.1};
OS   Amphiprion ocellaris (Clown anemonefish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000025239.1, ECO:0000313|Proteomes:UP000257160};
RN   [1] {ECO:0000313|Ensembl:ENSAOCP00000025239.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. RNA methyltransferase RlmE family.
CC       {ECO:0000256|ARBA:ARBA00009258}.
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DR   AlphaFoldDB; A0A3Q1CI58; -.
DR   STRING; 80972.ENSAOCP00000025239; -.
DR   Ensembl; ENSAOCT00000000753.1; ENSAOCP00000025239.1; ENSAOCG00000012664.1.
DR   GeneTree; ENSGT00730000111241; -.
DR   OMA; HRQTDHL; -.
DR   OrthoDB; 2785996at2759; -.
DR   Proteomes; UP000257160; Unplaced.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:UniProt.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProt.
DR   GO; GO:0001510; P:RNA methylation; IEA:InterPro.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   HAMAP; MF_01547; RNA_methyltr_E; 1.
DR   InterPro; IPR002877; RNA_MeTrfase_FtsJ_dom.
DR   InterPro; IPR015507; rRNA-MeTfrase_E.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR10920; RIBOSOMAL RNA METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR10920:SF18; RRNA METHYLTRANSFERASE 2, MITOCHONDRIAL; 1.
DR   Pfam; PF01728; FtsJ; 1.
DR   PIRSF; PIRSF005461; 23S_rRNA_mtase; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW   ECO:0000256|PIRSR:PIRSR005461-1};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          49..232
FT                   /note="Ribosomal RNA methyltransferase FtsJ"
FT                   /evidence="ECO:0000259|Pfam:PF01728"
FT   ACT_SITE        191
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR005461-1"
SQ   SEQUENCE   239 AA;  26787 MW;  49304D9A64648183 CRC64;
     MSLSCVQRRC FHSAVCLLKK QKSKTAAEQR WVLRQLRDPY VKASHAQNFR CRSAFKLLEI
     DDKFRLLQPG FSVVDCGAAP GAWSQVAVQR VNSAGTDPAL PRGTVVGIDL LYIPPLDGAH
     FLSSQDVTDP STHAKLLELL PNRQAHVMLS DMAPNASGFR DMDHEKLITM CLSLIDLAEK
     VLQPQGSLLC KYWDGILTRR LQEKLSSVFG GVRTLKPQAS RKDSAERYFL ATMYRKPMK
//