ID A0A3Q1CKN3_AMPOC Unreviewed; 883 AA.
AC A0A3Q1CKN3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Exocyst complex component 2 {ECO:0000256|ARBA:ARBA00017526, ECO:0000256|RuleBase:RU365069};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000026278.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000026278.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Component of the exocyst complex involved in the docking of
CC exocytic vesicles with fusion sites on the plasma membrane.
CC {ECO:0000256|ARBA:ARBA00002660, ECO:0000256|RuleBase:RU365069}.
CC -!- SUBUNIT: Component of the exocyst complex.
CC {ECO:0000256|RuleBase:RU365069}.
CC -!- SIMILARITY: Belongs to the SEC5 family. {ECO:0000256|ARBA:ARBA00010578,
CC ECO:0000256|RuleBase:RU365069}.
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DR AlphaFoldDB; A0A3Q1CKN3; -.
DR Ensembl; ENSAOCT00000017199.1; ENSAOCP00000026278.1; ENSAOCG00000014517.1.
DR GeneTree; ENSGT00390000010872; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0000145; C:exocyst; IEA:UniProtKB-UniRule.
DR GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR GO; GO:0006893; P:Golgi to plasma membrane transport; IEA:UniProtKB-UniRule.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd00603; IPT_PCSR; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR029175; EXOC2/Sec5.
DR InterPro; IPR039481; EXOC2/Sec5_N_dom.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR PANTHER; PTHR13043:SF1; EXOCYST COMPLEX COMPONENT 2; 1.
DR PANTHER; PTHR13043; EXOCYST COMPLEX COMPONENT SEC5; 1.
DR Pfam; PF15469; Sec5; 2.
DR Pfam; PF01833; TIG; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 3: Inferred from homology;
KW Exocytosis {ECO:0000256|ARBA:ARBA00022483, ECO:0000256|RuleBase:RU365069};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU365069};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365069}.
FT DOMAIN 8..91
FT /note="IPT/TIG"
FT /evidence="ECO:0000259|Pfam:PF01833"
FT DOMAIN 133..595
FT /note="Exocyst complex component EXOC2/Sec5 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF15469"
FT DOMAIN 665..873
FT /note="Exocyst complex component EXOC2/Sec5 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF15469"
SQ SEQUENCE 883 AA; 98976 MW; FEB044D25B49E3E8 CRC64;
MSRARQPPLV TGISPKEGAA WTKVTIRGEN LGTGPADLIG LSICGHNCLL TAEWMSASKI
VCRVGPAKDD KGEIIVTTKS GGLGTSTVSF KLIRPERIGI LDQSAVWVDE MNYYDMRTNR
NKGISPLSLR PSNPLGIEID KGKIPQKDME LTFPGMSGDF TSENFSATWY LIENHAGSSF
EQLKIAASNL KKQATKKNEG SLAYVKGGLS TFFEAQDALS AIHQRLESDG TEKVEGSMTQ
RLENILNRAS DTADTLFQEV LGRKDKADST RNALNVLQRF KFLFNLPLNI ERNIQKGDYD
VVINDYEKAK SLFGNTEVPV FKKVYAEVET RIGALRSLLL EKLLQTPSTL HDQKRYIRYL
SDLHAPGDPA WQCIYAQHKW ILQLMQNCRD EFISGQRGEE HPLEHSLGAG VLDLEGDTRP
SALGRLSHTA SLKRGGSLRT PRPSTWRFET PQQVQFVEKL SDVVIGQLPN FWKLWISYVN
GSLFSETGEK SGQVEKSKKN ARQRQNDFKK MIEELTNRLV KLIRGALLPT TLPQGELSLY
GGWENKTELT GAWLTQIIHT VRGCHDALSA LEIPNDLLQV IQDLLLELRV HCLMVTLLHT
TEAPAFHVCI CVLFLTFLQP SQFEQCMVQM LQSLKEPLEI KPGEINVRKF PATVNALIVA
RVAQVSEQRL LIILSNCQYL ERHTFLNLAD HFEKHGFTGT EKITRVNVDA VRELDRKLFD
AYIERRADPI AGSLEPGIYA GYFDWRDCQT PTGVRNYLKE ALVNIITVHA EVFTVSKDLV
PRVLSKIVES VADEMCRLMQ CVSSFSKNGA LQARLELCAL RDAVATYLNT DSNSSFKLAL
DALPQLHSGA DKKLLEELLN KFKSSMQLQL TCFQPSSIQP VKR
//
