ID A0A3Q1CPT8_AMPOC Unreviewed; 549 AA.
AC A0A3Q1CPT8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Sorting nexin 27 {ECO:0000313|Ensembl:ENSAOCP00000029987.1};
GN Name=SNX27 {ECO:0000313|Ensembl:ENSAOCP00000029987.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000029987.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000029987.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q1CPT8; -.
DR Ensembl; ENSAOCT00000024543.1; ENSAOCP00000029987.1; ENSAOCG00000020622.1.
DR GeneTree; ENSGT00950000183212; -.
DR OMA; SGLHCTG; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProt.
DR CDD; cd13338; FERM-like_C_SNX27; 1.
DR CDD; cd01777; FERM_F1_SNX27; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd06886; PX_SNX27; 1.
DR Gene3D; 1.20.80.60; -; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR037831; SNX17/27/31-like.
DR InterPro; IPR037827; SNX27_FERM-like_dom.
DR InterPro; IPR037833; SNX27_PX.
DR InterPro; IPR037835; SNX27_RA.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR12431; SORTING NEXIN 17 AND 27; 1.
DR PANTHER; PTHR12431:SF17; SORTING NEXIN 27B; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF00788; RA; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS50200; RA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW Transport {ECO:0000256|ARBA:ARBA00022927}.
FT DOMAIN 52..145
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 170..278
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT DOMAIN 282..371
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 549 AA; 62041 MW; 7041305615D03A8C CRC64;
MADVEEQGIC SSVPPLPHPS SRNGSGSGNV TPVTGGGGSC QTATTVTSGP RLVRIVKSDS
GYGFNVRGQV SEGGQLRSIN GELYAPLQHV SAVLPGGAAD RAGISKGDRI LEVNGVNVEG
ATHKQVVDLI RAGERELVLA VLSVPPQEAD CLDPGDDGSA QSCYDYSDKQ AVPISVPSYK
HTELNHEKFV VYNVYMAGRQ LCSKRYREFV ILHQNLKREF ANFTFPKLPG KWPFSLSEQQ
LDARRRGLEE YLEKVCSVRV IGESDIMQEF LSESDENYNG VSDVELRIAM PDKTTLTVRV
RKNSTTDQVY QAVVMKLGMD SVTASYFALF EVINHTFVRK LAPNEFPHKL YVQNYTSAIP
GTCLTLRKWL FTTEEEILLN DNQLAVSYFF HQAVDDVKKG FIKAEQKSYQ LQKLAEQKKT
SMYLSLLRGC EGYNEIIFPH CSCDSRRKGH VITAISIHHF KLHACTEDGT LENQVIAFDW
GEMQRWDTDE EGMAFCFEYA RGEKKPRWVK IFTPYFNYMH ECFERVFCEL KWRKENIFQL
LRHRRDGDT
//
