ID A0A3Q1CQM7_AMPOC Unreviewed; 475 AA.
AC A0A3Q1CQM7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2-like {ECO:0000313|Ensembl:ENSAOCP00000028083.1};
GN Name=BAIAP2 {ECO:0000313|Ensembl:ENSAOCP00000028083.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000028083.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000028083.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, ruffle
CC {ECO:0000256|ARBA:ARBA00004466}.
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DR AlphaFoldDB; A0A3Q1CQM7; -.
DR STRING; 80972.ENSAOCP00000028083; -.
DR Ensembl; ENSAOCT00000030840.1; ENSAOCP00000028083.1; ENSAOCG00000017506.1.
DR GeneTree; ENSGT00940000153560; -.
DR OMA; KNSYATX; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
DR GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR CDD; cd11915; SH3_Irsp53; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR013606; I-BAR_dom.
DR InterPro; IPR027681; IRSp53/IRTKS/Pinkbar.
DR InterPro; IPR035594; Irsp53_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14206; BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2; 1.
DR PANTHER; PTHR14206:SF3; BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF08397; IMD; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51338; IMD; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 36..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 50..227
FT /note="IMD"
FT /evidence="ECO:0000259|PROSITE:PS51338"
FT DOMAIN 337..400
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 401..431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 475 AA; 52399 MW; E34853AE0D1F3BD2 CRC64;
MCSVWLHGSF IVVFFCTMYV ALTDLISLSL LSPLPLFVYC LSCFCLVSAG EVLFQMAEVH
RQIQIQLEEM LKSFHNELLT ELEKKVELDA RYLNAALKKY QMEHKSKGES LEKCQAELKK
LRRKSQGSKH PSKYGDKEMQ YVEAISNKQS ELDNYIAEGY KNALSEERRR YCFLVDRQCA
VAKNSSTYHG KGKELLVQKI PMWQQACAEP NKLPDRAMFL AQQMSGAAGT LPPGAHHPGM
PISEPIPGAK PLPVPPELAA LRGGMPVMNG TAGAHGGDDY QQWMEGKIAQ GKASPQTQRH
GGEVYSNTLP VRKVAPAKAE TRTLPRSSSM AAGLERNGRT RVQAIFSHAA GDNSTLLSFA
EGDVITLLVP EARDGWHYGE NEKTRMRGWF PFSYTRVISD NEGDSSLHHG KSSSTGNLLE
REDMSLPGPD YGVHSRMAAP IAAALHGRQQ RPYSVAVPGF SQVGGQSDTK QAMNA
//
