ID A0A3Q1CSW8_AMPOC Unreviewed; 1720 AA.
AC A0A3Q1CSW8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=FERM and PDZ domain containing 3 {ECO:0000313|Ensembl:ENSAOCP00000031072.1};
GN Name=FRMPD3 {ECO:0000313|Ensembl:ENSAOCP00000031072.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000031072.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000031072.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 80972.ENSAOCP00000031072; -.
DR Ensembl; ENSAOCT00000026652.1; ENSAOCP00000031072.1; ENSAOCG00000022453.1.
DR GeneTree; ENSGT00950000183035; -.
DR OMA; VRDCKPY; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13183; FERM_C_FRMPD1_FRMPD3_FRMPD4; 1.
DR CDD; cd17169; FERM_F1_FRMPD3; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR049385; FAK1-like_FERM_C.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR041779; FRMPD1/3/4_FERM_C.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR46221:SF1; FERM AND PDZ DOMAIN-CONTAINING PROTEIN 3; 1.
DR PANTHER; PTHR46221; FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER; 1.
DR Pfam; PF21477; FERM_C_FAK1; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00295; B41; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50057; FERM_3; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000257160}.
FT DOMAIN 36..112
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 160..473
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 487..531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 564..587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 657..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 897..969
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 996..1023
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1080..1181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1280..1318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1687..1720
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 487..502
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 897..925
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 948..969
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1107..1127
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1720 AA; 188695 MW; 97CEDE94E32EC99C CRC64;
MAKVQDGHTN ACDTAMLEES QDGMDSGTLS PASARQVTIQ RHPTQGFGFV AGSQRPVIVR
SVSAGPSFGK LLPGDQILAI NEETVSDAPR ERVIDLVRCK DTIVLTVLQP HQSPKSAFIS
AAKKARLRTN PPKVRFSEQV SISDPDSTML KDDSLLLIPN VLKVFLENGQ IKSFTFDSRT
TVRDVISSLQ DRLSLRYIEH FALVLEAGGL DQNQRLHLLQ ENQPLTHVVH RTYFQGMKCL
FRICFFPKDP ADLLRRDPAA FEYLYIQSRN DVIKERFSMD WKSDITLRLA ALHIYITVSS
ARPNQKISLK HVKEWGLEPF LPLTLLPTVK EKNVCKTLSQ LLKTYQHPPP SGNKVPPLQG
KLQYMRVLND LPPFGGILFH TVGLDEKQSA TTLLVGPRHG ISHVIDLKNN LTTVLTEFSR
VSKIQLYRES QGVARVEVTI HEAKPLVLLM EWPDASNFAC LISGYYKLFV DPKRTIYFRT
PGQSQLTKAY RSSHNAHPRS GATSMPSGGR RGDERDSSHR ESGSSRAVVP AEPQHLGLCH
VHLREQHFQE LQTQAEAELD INENFISQEP SGRPRTKSDP TQHSTEEITG GLESPAVENA
GFRIRAQTVG QSQKTSRYFC DSCKARLRAE GLSTGVNSSG SSGKHCSGAC ASRNGGAVDL
MALPPPGNEE EDEEEVDGGG EKLQPPPPAI AAPPPGFRDN SSDEDDQKRG RKAQTSATAG
VACGKLAEAK EDVPVTLIDN VATRTVRDHA QELDDALVST LQALEALAAS EDYPHHPQQP
TQTALIVLAA ITPESSLDSG HETNSSELTD VSEMVSAMKQ NQNQAYLLAH HINKERILCR
RDFPLAIPGC TAKTIGSGAF SVGQIRAGCP PKQVILSKTV PFKVSPNQES AILSVMTEQG
SNQDTTQTEQ KAEIKANSES TKANTPDPPS KPPEELKVSD ASLAAQVSKD HKLSNSSAET
LSQNLSDGIK GKTTGLLNTD ATNKALPILL PVDRTASAKS SPSNMCQDAK TASSKTMKPS
SSTELLPVDD LFCTCPVQQE PGPQLRLKDP QVQKIVVFQS SSPTDDERLQ AKGLQLANSK
ENAVRAGVDP SLAKPSPQIQ TKYSPRLPSK AERKEAAESK TESAQGKSHP ESQKCPIKSL
PILDDPTTPS PSVDKVSTLP ARDTKKQGSG KGKSQRSAPF LSFRNLLSAT FPARMRRETD
ERRAQLQKVR QYELEFLEEL LKPKSSQGEF LPQGSSPVPS GTPCACQLRT SPVLKAPGIS
REQRRSCDCK RMCRGMRLPD TPVGSTTETQ NRGRERTISK TPPAVSKAPH AQGATRRPQT
LEIKTTRIRS TSLESREPRG EQGSCLPTCT SETDCMGAPQ YKKLQRRYSI GELDNSTSTP
VYAEVKPKAK SLEKEMERVR ATGLRLPTPV EPVHTQSHQA EGKGKRGVFF IQGEELLRES
KEGTGEVLLT LPCEDSDDKD KCCSFCFCYR KCEAADESSE KDELSYSIPL QVLPGMELDS
RTFPVVSKTL QVLNAEDCSG EEEEEEEEEP QAQEIDLRAC GTLEGSLARV QALQGKTFSL
PDGFLNAQLD ANELLAILRQ CANSPQAEGE ARLQPSRIAE YKQELAVRFK EFRASCRRVA
SVEKSPTRML AVVSASFQVL CELTQTFIKL VRGVRSETQR LQLLRKVEEV AINYTLLLRA
AEESMGHSSS LPTKTVSPQV SSNTNNMSSL TRPIKTLPAQ
//
