ID   A0A3Q1CVA6_AMPOC        Unreviewed;       956 AA.
AC   A0A3Q1CVA6;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=General vesicular transport factor p115 {ECO:0000256|ARBA:ARBA00018243};
OS   Amphiprion ocellaris (Clown anemonefish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000031887.1, ECO:0000313|Proteomes:UP000257160};
RN   [1] {ECO:0000313|Ensembl:ENSAOCP00000031887.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC       Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC   -!- SIMILARITY: Belongs to the VDP/USO1/EDE1 family.
CC       {ECO:0000256|ARBA:ARBA00006960}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3Q1CVA6; -.
DR   Ensembl; ENSAOCT00000028279.1; ENSAOCP00000031887.1; ENSAOCG00000023936.1.
DR   GeneTree; ENSGT00390000017018; -.
DR   OMA; LLDYEYC; -.
DR   Proteomes; UP000257160; Unplaced.
DR   GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000225; Armadillo.
DR   InterPro; IPR041209; P115_Arm_rpt.
DR   InterPro; IPR006955; Uso1_p115_C.
DR   InterPro; IPR006953; Vesicle_Uso1_P115_head.
DR   PANTHER; PTHR10013; GENERAL VESICULAR TRANSPORT FACTOR P115; 1.
DR   PANTHER; PTHR10013:SF0; GENERAL VESICULAR TRANSPORT FACTOR P115; 1.
DR   Pfam; PF18770; Arm_vescicular; 1.
DR   Pfam; PF04871; Uso1_p115_C; 1.
DR   Pfam; PF04869; Uso1_p115_head; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50176; ARM_REPEAT; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          60..97
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   DOMAIN          346..633
FT                   /note="Vesicle tethering protein Uso1/P115-like head"
FT                   /evidence="ECO:0000259|Pfam:PF04869"
FT   DOMAIN          843..951
FT                   /note="Uso1/p115-like vesicle tethering protein C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04871"
FT   REGION          715..734
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          819..839
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          929..956
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          657..705
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        933..956
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   956 AA;  106775 MW;  A92210E74C00AAAA CRC64;
     MNFFRGVMGG QAAGPQPSGA ETIQKLCDRV ASSTLLEDRR DAVRALKSLS KKYRMEVGTQ
     AMDHLINILQ TDRSDSEILG YALDTLYNII CNDEEEEQDE NAQKQADDLG AQFTDKFIQD
     PEHITLLLTL LEEFDFHVRW PGVKLLTALL KNQGVQVQGI ILVSPMGVSR LMDLLADSRE
     VIRNDGLLLL QQLTKGNAAI QKIVAFENAF ERLLDIITEE GSSDGGIVVE DCLLLLLNLL
     KNNSSNQNFF KEGSYIQRMK PWFEVGDDNA GWSAQKVTNL HLMLQLVRVM VSPVNSPGAT
     ASCQKSMYQC DLLQQLCTIL MATGVPADIL TETINTVSEV IRGSQVNQDY FASVNAPSNP
     PRPAIVVLLM SMVNERQPFV LRCAVLYCFQ CFLYKNQKGQ GEIVATLLPS TIDANSISAG
     QLLCGGLFSA DSLSNWCAAV ALAHALQDNL TQKEQLLRVQ LATSLGKPPV SLLQQCTNIL
     SQGDKIVRRG SKVQTRVGLL MLLCTWISNC PIAVTHFLHN QENVPFLTAQ ISENLGEDER
     LVQGLCALLL GICIYYNDNS LENYTKEKLK QLIEKRIGKE NFVEKLGFIT KHELYSRAAQ
     KPQPVFPSPE QMLFDHEFTK LVKELEGVIT KAVHKSTEEE KKEEEVKKTL EQHDNIVTQY
     KELIREQDAQ IQELKEQVAS MTSQNEQMQT TVTQQLSQIQ QHKDQYNILK LKLGKENQSQ
     SSSQGDGSQM NGLQTEELSQ LREEVEELRK QHSLLQTQLG DKDALINTLK SGASQTADGP
     AGGSDNTELL QELEALRNQV QSQSTEITQL KTERQDLLRK AEAGSSDTAV PTSDGSLDGA
     KMAELEGRLT AQMSETQRLE EEVKRLSESR AELEQQLASS TSTVAILQTE KTKLQTEVQE
     SKKEQDDLLM LLADQDQKIH NLKQRLKDLG ETVEDEDDLD ARDQTDDDDE EDEDED
//