ID   A0A3Q1CVD2_AMPOC        Unreviewed;       397 AA.
AC   A0A3Q1CVD2;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Clusterin {ECO:0000256|RuleBase:RU000629};
OS   Amphiprion ocellaris (Clown anemonefish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000031175.1, ECO:0000313|Proteomes:UP000257160};
RN   [1] {ECO:0000313|Ensembl:ENSAOCP00000031175.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the clusterin family.
CC       {ECO:0000256|ARBA:ARBA00010069, ECO:0000256|RuleBase:RU000629}.
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DR   AlphaFoldDB; A0A3Q1CVD2; -.
DR   Ensembl; ENSAOCT00000026898.1; ENSAOCP00000031175.1; ENSAOCG00000022656.1.
DR   GeneTree; ENSGT00530000063668; -.
DR   Proteomes; UP000257160; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR000753; Clusterin-like.
DR   InterPro; IPR016015; Clusterin_C.
DR   InterPro; IPR016014; Clusterin_N.
DR   PANTHER; PTHR10970; CLUSTERIN; 1.
DR   PANTHER; PTHR10970:SF2; CLUSTERIN-LIKE PROTEIN 1; 1.
DR   Pfam; PF01093; Clusterin; 2.
DR   SMART; SM00035; CLa; 1.
DR   SMART; SM00030; CLb; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          1..201
FT                   /note="Clusterin N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00030"
FT   DOMAIN          218..384
FT                   /note="Clusterin C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00035"
FT   COILED          14..65
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   397 AA;  45187 MW;  CF9C2342937F6AA6 CRC64;
     QYVDEEIKQT LLGVKQMKEM MEKKEEKHRH LMDALRHSSD KKKLAKETEQ KLDEAEQKCR
     DLTKSSFGKC RPCVEESCKA FYTSTCRRGF ASFSFKVEEF FRKMAAQLEA SEHVYNQNQE
     NSDRTSSAEI TEDKSHLDLL QAEASFSQLL SNISLLYDHS VTVVQKMQQV FGRSFQASFT
     SELQPGLLSA VQGEPSAGFL RTVGLDHIFD SVFDFGKNVV EKFSSSMADV FEEMHEAEEY
     LQQGMRGSLS LQNLYHFFPS PLSECPSVQP LHSEMEEMNM LLNASRRQYD DRLQLVQRHT
     ADTQKWLSSM DDKFGWIGQL SGSTVEPKSI FSQRMRNNKP KADSTVVVSI LDSTPVTILV
     PADLEVDDPA FIQFVAQEAL TLHKRQNKGN DPTSEAL
//