ID   A0A3Q1CZ57_AMPOC        Unreviewed;       673 AA.
AC   A0A3Q1CZ57;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Rhophilin Rho GTPase binding protein 2 {ECO:0000313|Ensembl:ENSAOCP00000031203.1};
OS   Amphiprion ocellaris (Clown anemonefish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000031203.1, ECO:0000313|Proteomes:UP000257160};
RN   [1] {ECO:0000313|Ensembl:ENSAOCP00000031203.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the RHPN family.
CC       {ECO:0000256|ARBA:ARBA00010369}.
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DR   AlphaFoldDB; A0A3Q1CZ57; -.
DR   Ensembl; ENSAOCT00000032773.1; ENSAOCP00000031203.1; ENSAOCG00000002561.1.
DR   GeneTree; ENSGT00940000153837; -.
DR   Proteomes; UP000257160; Unplaced.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd00136; PDZ; 1.
DR   Gene3D; 2.30.42.10; -; 1.
DR   Gene3D; 1.25.40.280; alix/aip1 like domains; 1.
DR   Gene3D; 1.10.287.160; HR1 repeat; 1.
DR   InterPro; IPR004328; BRO1_dom.
DR   InterPro; IPR038499; BRO1_sf.
DR   InterPro; IPR011072; HR1_rho-bd.
DR   InterPro; IPR036274; HR1_rpt_sf.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR041489; PDZ_6.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR047138; RHPN1_2.
DR   PANTHER; PTHR23031; RHOPHILIN; 1.
DR   PANTHER; PTHR23031:SF5; RHOPHILIN-2-RELATED; 1.
DR   Pfam; PF03097; BRO1; 1.
DR   Pfam; PF02185; HR1; 1.
DR   Pfam; PF17820; PDZ_6; 1.
DR   SMART; SM01041; BRO1; 1.
DR   SMART; SM00742; Hr1; 1.
DR   SMART; SM00228; PDZ; 1.
DR   SUPFAM; SSF46585; HR1 repeat; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 1.
DR   PROSITE; PS51180; BRO1; 1.
DR   PROSITE; PS50106; PDZ; 1.
DR   PROSITE; PS51860; REM_1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01207};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257160}.
FT   DOMAIN          11..85
FT                   /note="REM-1"
FT                   /evidence="ECO:0000259|PROSITE:PS51860"
FT   DOMAIN          96..445
FT                   /note="BRO1"
FT                   /evidence="ECO:0000259|PROSITE:PS51180"
FT   DOMAIN          501..569
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
SQ   SEQUENCE   673 AA;  75981 MW;  899B0E4B09861051 CRC64;
     MTDVIVPYGC NPFAQTGRSK LQNKRASLNQ QIIKQMRMRA GAENLLKATS NNKVKEMVLL
     ELSYVNSNLQ LLTGQLEGLN SSVEVYQNTQ ETANIPLIAL GLKETKEVDF STPFKDFILE
     HYSEDRNSFE DEIADLMDLR QACRTPSRNE VGVELLAKYY SHLPLIESRF FSPSRQTGIF
     FTWYDSFTGV PLCQQNLSLE KASILFNMAA LYSQIGTRSD RQTISGLEEA ISSFQKAAGI
     LNHLKETFTH TPSYDMSPAM LSMLIRMMLA QAQECLFEKT ALPGIRNQFY SLMKMAQEAA
     KVSEIYDQVH QSMIQMPIKD NVPLFWSTMS QVKANHYRSM AHYFVASALL DHQLSPSDDE
     DQQEKTLSQV YDRIPEGRSP LDILKKKDER QCVGKAHIRR AILGHEEALR IYSLCHNLNK
     LEILQDILKA SHQRSLNKFS EHEDEDEFTD YTEAPDIISK TEHKAEMEVP ATTKVKVIDF
     FQRLGPLSVF SAKQRWTAPR TIQLQPQDRD LGFTLKGESP VQVVSLDPLC PAAADGLKEG
     DYIVAVGDTE CKWMGVSEVM RLLKDVDEEG IEIQVVSMMD TNPPMPTKSA TFCGNLPKTY
     SMICLGYDDN DKNPKSHKVT KKSSFLSWGL KNKLKSASTL SLPTADHSGT LPWNKPCPTF
     PSSSSYNNDS SLY
//