ID A0A3Q1CZL1_AMPOC Unreviewed; 593 AA.
AC A0A3Q1CZL1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Prickle planar cell polarity protein 3 {ECO:0000313|Ensembl:ENSAOCP00000031378.1};
GN Name=PRICKLE3 {ECO:0000313|Ensembl:ENSAOCP00000031378.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000031378.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000031378.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the prickle / espinas / testin family.
CC {ECO:0000256|ARBA:ARBA00008268}.
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DR AlphaFoldDB; A0A3Q1CZL1; -.
DR Ensembl; ENSAOCT00000032879.1; ENSAOCP00000031378.1; ENSAOCG00000023058.1.
DR GeneTree; ENSGT00940000153629; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd09415; LIM1_Prickle; 1.
DR CDD; cd09418; LIM2_Prickle; 1.
DR CDD; cd09420; LIM3_Prickle; 1.
DR CDD; cd09827; PET_Prickle; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 3.
DR InterPro; IPR033725; LIM1_prickle.
DR InterPro; IPR033726; LIM2_prickle.
DR InterPro; IPR033727; LIM3_prickle.
DR InterPro; IPR010442; PET_domain.
DR InterPro; IPR033723; PET_prickle.
DR InterPro; IPR047120; Pk/Esn/Tes.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24211; LIM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24211:SF19; PRICKLE PLANAR CELL POLARITY PROTEIN 3; 1.
DR Pfam; PF00412; LIM; 3.
DR Pfam; PF06297; PET; 1.
DR SMART; SM00132; LIM; 3.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 2.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 2.
DR PROSITE; PS51303; PET; 1.
PE 3: Inferred from homology;
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 69..177
FT /note="PET"
FT /evidence="ECO:0000259|PROSITE:PS51303"
FT DOMAIN 179..243
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 244..304
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 372..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 456..593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 465..496
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..529
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 547..569
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..593
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 593 AA; 67359 MW; EBF1AFD0F130AF7C CRC64;
CFALSLCCFQ QEEEDPDKGQ PCMRCGDQCP GFRVHGWRKI CVHCKCVREE HAVRSVPGQL
EKMMTKLVSD FQRHSISDDD SGCASEEYAW VPPGLKPEQV YQYFSCLPED RVPYVNSLGE
RYRIKQLLHQ LPAHDSEPQY CNSLDEQEKK ELCLFSQQRK RENLGRGIVR LFPVTMTGAI
CLQCGRQICG GDIAVFASRA GHSSCWHPQC FQCASCSELL VDLIYFYQDG QIYCGRHHAE
RLKPRCQACD EIILADECTE AEGRYWHMKH FCCFECEAAL GGQRYIMRES RPYCCSCYES
LYAEYCDTCG EHIGIDQGQM TYEGQHWHAV ESCFCCARCR LPLLGRPFLP RGGLIFCSRP
CSLGEDPNNS DSCDSALQSR PPHHNRRSGT EKRHQLQCGS PLQPLEEKQN VIHGTSVVPG
FTGTPSQVHG VWLTVSFFQS DGSSYQQRGL RRGWSRCRIP SDPALHQSSE RRSRRSRPDR
PHLDTLDWRG EKERDTWGPS NSSSLTLQQG HYKHGDSCST CSSSSDSEEE GYFLGKPIPV
PPQLRKQEPE GGKDREADEG KEVRRDKGLR GSIRRRRAHS LGAKDKDKNC AIS
//
