ID   A0A3Q1CZW2_AMPOC        Unreviewed;       687 AA.
AC   A0A3Q1CZW2;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Rhophilin Rho GTPase binding protein 2 {ECO:0000313|Ensembl:ENSAOCP00000031229.1};
OS   Amphiprion ocellaris (Clown anemonefish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000031229.1, ECO:0000313|Proteomes:UP000257160};
RN   [1] {ECO:0000313|Ensembl:ENSAOCP00000031229.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the RHPN family.
CC       {ECO:0000256|ARBA:ARBA00010369}.
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DR   AlphaFoldDB; A0A3Q1CZW2; -.
DR   STRING; 80972.ENSAOCP00000031229; -.
DR   Ensembl; ENSAOCT00000026958.1; ENSAOCP00000031229.1; ENSAOCG00000002561.1.
DR   GeneTree; ENSGT00940000153837; -.
DR   OMA; HTAMSQA; -.
DR   OrthoDB; 24567at2759; -.
DR   Proteomes; UP000257160; Unplaced.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd00136; PDZ; 1.
DR   Gene3D; 2.30.42.10; -; 1.
DR   Gene3D; 1.25.40.280; alix/aip1 like domains; 1.
DR   Gene3D; 1.10.287.160; HR1 repeat; 1.
DR   InterPro; IPR004328; BRO1_dom.
DR   InterPro; IPR038499; BRO1_sf.
DR   InterPro; IPR011072; HR1_rho-bd.
DR   InterPro; IPR036274; HR1_rpt_sf.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR041489; PDZ_6.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR047138; RHPN1_2.
DR   PANTHER; PTHR23031; RHOPHILIN; 1.
DR   PANTHER; PTHR23031:SF5; RHOPHILIN-2-RELATED; 1.
DR   Pfam; PF03097; BRO1; 1.
DR   Pfam; PF02185; HR1; 1.
DR   Pfam; PF17820; PDZ_6; 1.
DR   SMART; SM01041; BRO1; 1.
DR   SMART; SM00742; Hr1; 1.
DR   SMART; SM00228; PDZ; 1.
DR   SUPFAM; SSF46585; HR1 repeat; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 1.
DR   PROSITE; PS51180; BRO1; 1.
DR   PROSITE; PS50106; PDZ; 1.
DR   PROSITE; PS51860; REM_1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01207};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257160}.
FT   DOMAIN          25..99
FT                   /note="REM-1"
FT                   /evidence="ECO:0000259|PROSITE:PS51860"
FT   DOMAIN          110..459
FT                   /note="BRO1"
FT                   /evidence="ECO:0000259|PROSITE:PS51180"
FT   DOMAIN          515..583
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
SQ   SEQUENCE   687 AA;  77400 MW;  B796205805E6E6C3 CRC64;
     MTDALLPNGI KDGGGDSTYF RKGCNPFAQT GRSKLQNKRA SLNQQIIKQM RMRAGAENLL
     KATSNNKVKE MVLLELSYVN SNLQLLTGQL EGLNSSVEVY QNTQETANIP LIALGLKETK
     EVDFSTPFKD FILEHYSEDR NSFEDEIADL MDLRQACRTP SRNEVGVELL AKYYSHLPLI
     ESRFFSPSRQ TGIFFTWYDS FTGVPLCQQN LSLEKASILF NMAALYSQIG TRSDRQTISG
     LEEAISSFQK AAGILNHLKE TFTHTPSYDM SPAMLSMLIR MMLAQAQECL FEKTALPGIR
     NQFYSLMKMA QEAAKVSEIY DQVHQSMIQM PIKDNVPLFW STMSQVKANH YRSMAHYFVA
     SALLDHQLSP SDDEDQQEKT LSQVYDRIPE GRSPLDILKK KDERQCVGKA HIRRAILGHE
     EALRIYSLCH NLNKLEILQD ILKASHQRSL NKFSEHEDED EFTDYTEAPD IISKTEHKAE
     MEVPATTKVK VIDFFQRLGP LSVFSAKQRW TAPRTIQLQP QDRDLGFTLK GESPVQVVSL
     DPLCPAAADG LKEGDYIVAV GDTECKWMGV SEVMRLLKDV DEEGIEIQVV SMMDTNPPMP
     TKSATFCGNL PKTYSMICLG YDDNDKNPKS HKVTKKSSFL SWGLKNKLKS ASTLSLPTAD
     HSGTLPWNKP CPTFPSSSSY NNDSSLY
//