ID A0A3Q1D0Y7_AMPOC Unreviewed; 1089 AA.
AC A0A3Q1D0Y7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=SLIT-ROBO Rho GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSAOCP00000031624.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000031624.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000031624.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q1D0Y7; -.
DR STRING; 80972.ENSAOCP00000031624; -.
DR Ensembl; ENSAOCT00000033052.1; ENSAOCP00000031624.1; ENSAOCG00000023449.1.
DR GeneTree; ENSGT00950000182824; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04383; RhoGAP_srGAP; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14166; SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR14166:SF15; SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 1; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|PROSITE-
KW ProRule:PRU01077}; Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 19..319
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 478..676
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT DOMAIN 725..784
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 701..725
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 790..936
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 978..1089
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 357..384
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 801..815
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 824..842
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 846..860
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 884..914
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 992..1040
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1061..1089
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1089 AA; 122015 MW; 7EBB68BDFD114079 CRC64;
MSNSNKSKKD KEILAEYESQ VKDVRTQLVE QQRCLEQQTE MRVQLLQDLQ DFFRKKAEIE
TEYSRNLEKL AERFMAKTRS TKDHQQYKKD QNLLSPVNCW YLLLNQVRRE SKDHATLSDL
YLNNVITRLT HISEDSARLL KRSKEIIFQL QEDLMKLLNE LYTVMKTYHM YHAETINAET
KLREAERQEG RVKGVSGSGG GVEPVFGLRI EERHQRRNAA RKMEKMREKR KAKYSENKLK
ALKARNEYLL TLEATNASVF KYYIHDLPDI IDCCDLGYHS SLSRSLRTYL SAELSLEASR
RAGLEVLEGA VEGLDPARDR QRLLGLYPTA FCPPQRFSFQ AHMGDAVTQI ASQPQVQAEL
TLRLTQLQTR LASLKIENEE VKKTWGATLT TLQDMTVLDD YDVSQSFTHS PSSESVKSSV
SDGYLNKPSL AKRRANQQET ELFYFTKFRE YLEGSNLISK LQAKHDILKK ALAEGYKAEL
LTTSRGRKNS HSKHQDSTKA IPLLVESCIR YINLHGLQHQ GIFRVSGSQV EVNDIKNSFE
RGNDPLIDEE SNHDINSVAG VLKLYFRGLE NPLFPKDRFN DLISCIRIEN MYERAQCIRK
ILLGVPRATL VVMRYLFAFL NHLSQYSDEN MMDAGNLAIV FGPTLLPTPD TLDQVACQAH
VNEVIKTVIL NHDNIFPDTK ELPGPVYEKC MTGDQYCESP FSEPGALEEA EPDAGTETQT
SDEEGEAVEA VARFDYVGRS GRELSFKKGA SLQLFQRASH DWWEGRHNGS IGLVPHQYIV
VKDRADAMSD TLSQKADSDG GSSSTDDKRS RSELSSPTDI RPPDTYNSHR RKRTDGLFRR
PLCRSNDNHG NGNVMERSSP PVTGHFSPRE LLLGRGQGLT PPLDSPERRR RSAAVTMTVS
RHDSLRRPED TPIRRSSSGQ HGFNDNHRSR AIDPDTLAQD IEESVTVALG ELRQLERQGC
RPAPDVVLDT LEQVKNGPVT ACSSESPSPH STPSTPGTPG TPGTPGTPGT PGTPSPLSPL
SPISPLPGPP PGPPRPANPS PDALGSFKPV AAARIGAPLR PPALRPKPMV PPKSSTPPLP
PPLDKSCTM
//
