ID A0A3Q1D188_AMPOC Unreviewed; 140 AA.
AC A0A3Q1D188;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Endothelin 2 {ECO:0000313|Ensembl:ENSAOCP00000032028.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000032028.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000032028.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the endothelin/sarafotoxin family.
CC {ECO:0000256|ARBA:ARBA00010959}.
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DR AlphaFoldDB; A0A3Q1D188; -.
DR Ensembl; ENSAOCT00000028560.1; ENSAOCP00000032028.1; ENSAOCG00000024095.1.
DR GeneTree; ENSGT00950000183053; -.
DR OMA; CRASPRD; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0019229; P:regulation of vasoconstriction; IEA:InterPro.
DR GO; GO:0042310; P:vasoconstriction; IEA:UniProtKB-KW.
DR InterPro; IPR020475; Endothelin.
DR InterPro; IPR019764; Endothelin_toxin_CS.
DR InterPro; IPR001928; Endothln-like_toxin.
DR PANTHER; PTHR13874; ENDOTHELIN; 1.
DR PANTHER; PTHR13874:SF9; ENDOTHELIN-2; 1.
DR Pfam; PF00322; Endothelin; 1.
DR PRINTS; PR00365; ENDOTHELIN.
DR SMART; SM00272; END; 2.
DR PROSITE; PS00270; ENDOTHELIN; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Vasoactive {ECO:0000256|ARBA:ARBA00022858};
KW Vasoconstrictor {ECO:0000256|ARBA:ARBA00023322}.
FT DOMAIN 52..73
FT /note="Endothelin-like toxin"
FT /evidence="ECO:0000259|SMART:SM00272"
FT DOMAIN 98..119
FT /note="Endothelin-like toxin"
FT /evidence="ECO:0000259|SMART:SM00272"
SQ SEQUENCE 140 AA; 15909 MW; 9281F427FDFFBF89 CRC64;
GADLNTKHLL LLSSLNTHRT SGTLLVYQSC GLPLSARSEL AVQAPHRVRT KRCSCNSWDD
KECIYFCHLD IIWVNTPSKL LPYGLGSPPS RRRRSADRCE CLNSADKKCH GFCRKRQSFG
RLRRLKPMMS NDDSECRVIS
//
