ID A0A3Q1D4K9_AMPOC Unreviewed; 910 AA.
AC A0A3Q1D4K9;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Metabotropic glutamate receptor 7-like {ECO:0000313|Ensembl:ENSAOCP00000025956.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000025956.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000025956.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family.
CC {ECO:0000256|ARBA:ARBA00007242}.
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DR AlphaFoldDB; A0A3Q1D4K9; -.
DR Ensembl; ENSAOCT00000016549.1; ENSAOCP00000025956.1; ENSAOCG00000013897.1.
DR GeneTree; ENSGT01030000234648; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15451; 7tmC_mGluR7; 1.
DR CDD; cd06376; PBP1_mGluR_groupIII; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR001883; GPCR_3_mGluR7.
DR InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR24060:SF98; METABOTROPIC GLUTAMATE RECEPTOR 7; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01057; MTABOTROPC7R.
DR PRINTS; PR00593; MTABOTROPICR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00979; G_PROTEIN_RECEP_F3_1; 1.
DR PROSITE; PS00980; G_PROTEIN_RECEP_F3_2; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..47
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 48..910
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018520940"
FT TRANSMEM 600..626
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 638..658
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 670..691
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 764..785
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 797..819
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 839..861
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 600..874
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 886..910
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 910 AA; 101329 MW; 8B66AD4E8756504C CRC64;
MNCWISETLQ RSAASVPNPV MARRSGRPPQ LLRFLWLLQA LLDLAGSQEI YAPHSIRVEG
DVTLGGLFPV HARGVPGMPC GDIKKENGIH RLEAMMYALD QINGDDELLP NVTLGARVLD
TCSRDTYALE QSLTFVQALI QKDTSDVRCT NGEPPVFVKP EKVVGVVGAS ASSVSIMVAN
ILRLFQIPQI SYASTAPELS DDRRYDFFSR VVPPDSFQAQ AMVDIVKAMG WNYVSTVASE
GSYGEKGVDA FMQLSREAGG ICIAQSLKIP HDHKPSDFDK IIRLLLETRY ARAVILFASD
EDIRGVLNAS KRADQVGHFL WIGSDSWGAK NSPIYQLEEA AVGAITILPK RATISGFDAY
FTSRTLENNR RNVWFAEYWE ENFNCKLMSS SKKDDSSRKC TGQERIGIDS KYEQEGKVQF
VIDAVYAMAH ALHNMQRDLC PENSGICPEM DLAGGKKLLK YIRSVSFNGS AGTSVTFNRN
GDAPGRYDLF QYQWNNVSGP GYRVIGQWTE TLQLNMEDMQ WPRGEQDVPT SVCSLPCKAG
ERKKVVKGMP CCWHCEPCDG YQYQPDEFNC KLCSYNMRPS TNRSSCQPIP IIKLEWHSPW
AVIPVFLAML GIVATIFVMA TFVRYNDTPI VRASGRELSY VLLTGIFLCY IITFLMIAKP
DVGVCSFRRI FLGLGMCISY AALLTKTNRI YRIFEQGKKS VTAPRLISPT SQLAITSSLI
SVQLLGVLVW FSVDPPNTIV DYDEQKTINP DLARGVLKCD ITDLQIICSL GYSILLMVTC
TVYAIKTRGV PENFNEAKPI GFTMYTTCIV WLAFIPIFFG TAQSAEKLYI QTTTLTISMN
LSASVALGML YMPKVYVIIF HPELNVQKRK RSFKAVVTAA TMSTRLSHKA SDRPNGEAKT
ELCENVDPNS
//
