ID A0A3Q1D9G8_AMPOC Unreviewed; 292 AA.
AC A0A3Q1D9G8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Vascular endothelial growth factor D {ECO:0000313|Ensembl:ENSAOCP00000027621.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000027621.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000027621.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PDGF/VEGF growth factor family.
CC {ECO:0000256|RuleBase:RU003818}.
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DR AlphaFoldDB; A0A3Q1D9G8; -.
DR STRING; 80972.ENSAOCP00000027621; -.
DR Ensembl; ENSAOCT00000030579.1; ENSAOCP00000027621.1; ENSAOCG00000016720.1.
DR GeneTree; ENSGT00940000159726; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR GO; GO:0008015; P:blood circulation; IEA:Ensembl.
DR GO; GO:0001946; P:lymphangiogenesis; IEA:Ensembl.
DR CDD; cd00135; PDGF; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR023581; PD_growth_factor_CS.
DR InterPro; IPR000072; PDGF/VEGF_dom.
DR PANTHER; PTHR12025; VASCULAR ENDOTHELIAL GROWTH FACTOR; 1.
DR PANTHER; PTHR12025:SF11; VASCULAR ENDOTHELIAL GROWTH FACTOR D; 1.
DR Pfam; PF00341; PDGF; 1.
DR SMART; SM00141; PDGF; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00249; PDGF_1; 1.
DR PROSITE; PS50278; PDGF_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|RuleBase:RU003818};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160}.
FT DOMAIN 126..224
FT /note="Platelet-derived growth factor (PDGF) family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50278"
SQ SEQUENCE 292 AA; 34021 MW; 4728D54AB80EFEA4 CRC64;
MFLRKIFHIS FFPPKNVERF SRNVENVDIR SFTVKIFFFL HILKQVNFDP QDDMRVKLHE
KQWERKVRSS SSLDELLRLA DFPDWKLWKC RLRLQQPETQ TENLSSPPSV GSHRSTRYAA
ESYSLEILKA IDEEWQRTQC MPRETCVDVA KELGTDPSMF FKPPCVSVHR CSGCCNQEGV
TCRNTTTVYV NKTVLSVIPF KFVPEPVLIK VANHTECRCM EPAIIRRNAQ PHRKIEDSRR
LCASGSIWDC SSDRCIPYPS STLGVWIFFV KLHFQAHICG HEQLLGRLHK CS
//
