ID A0A3Q1DA22_AMPOC Unreviewed; 649 AA.
AC A0A3Q1DA22;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Leucine rich repeat, Ig-like and transmembrane domains 1 {ECO:0000313|Ensembl:ENSAOCP00000027881.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000027881.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000027881.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q1DA22; -.
DR STRING; 80972.ENSAOCP00000027881; -.
DR Ensembl; ENSAOCT00000020428.1; ENSAOCP00000027881.1; ENSAOCG00000017149.1.
DR GeneTree; ENSGT00940000156033; -.
DR OMA; KYIVCVC; -.
DR OrthoDB; 3678698at2759; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45842:SF9; LEUCINE-RICH REPEAT, IMMUNOGLOBULIN-LIKE DOMAIN AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR45842; SYNAPTIC ADHESION-LIKE MOLECULE SALM; 1.
DR Pfam; PF00041; fn3; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13855; LRR_8; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SMART; SM00369; LRR_TYP; 4.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..649
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018676038"
FT TRANSMEM 550..575
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 251..343
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 453..541
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
SQ SEQUENCE 649 AA; 70955 MW; 6D5C3FB395F8BE1B CRC64;
MSRHFTAAFI LAVVFLPLLC SSCPVQCSCF FHKLSDGSKA RSVLCNDPEI TVVPPNFPLD
TSKLRIEKTA ITRISSNNFH YLNSLEFLWM SFNSLSSLNV DSFRGLYNLD ELRLDGNALT
SFPWESLTDM PNLRLLDLHN NKISSIPPEA TMYIKNITYL DLSSNSLTTV PTEILTMWLS
MKPSSDSESK LILGLHDNPW LCDCRLYDLV QFQKSPSSSV ALIDTRLRCA DPESLSGVLF
TEAELQRCQG PRVHTAVARV RSSLGNNVLL RCGTVGVPIP ELSWSRADGK KMNGTVQEEI
SKEGIIWSIL SVPAVSYRDS GKYVCKATNF VGTADAIISL VITDSLRADE AGGGVSKRTR
GKKPGGIGRA AYQEKLIARY VPPPTATAAQ PIIEPLNSKG VTGKYEIESY SISDDASQTR
GKASEDQKPV EVDALSNLAA NASSLQQAPE KRIVRSVKVI GDTDHTVSLN WRAPTATNTT
EFSVLYAIFG ERDMRRINVG AGKNRITIDG LVPKTKYIAC VCVKGLIPKK EQCVIFSTDE
AASASGTQKL INVVVITVAC VIAVPLTLIV CCGAIKKRCQ KLLGRQSKEI QDSYVTFETL
GPAAKAKGME GEYLTRLNPD ESNRLLSARS SIDSEATVRT EGPPNEYFC
//
