ID   A0A3Q1E999_9TELE        Unreviewed;       514 AA.
AC   A0A3Q1E999;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Sorting nexin 2 {ECO:0000313|Ensembl:ENSAPOP00000000236.1};
GN   Name=SNX2 {ECO:0000313|Ensembl:ENSAPOP00000000236.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000000236.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000000236.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the sorting nexin family.
CC       {ECO:0000256|ARBA:ARBA00010883}.
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DR   AlphaFoldDB; A0A3Q1E999; -.
DR   STRING; 80966.ENSAPOP00000000236; -.
DR   Ensembl; ENSAPOT00000017201.1; ENSAPOP00000000236.1; ENSAPOG00000001431.1.
DR   GeneTree; ENSGT00940000155798; -.
DR   InParanoid; A0A3Q1E999; -.
DR   OrthoDB; 1891044at2759; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   InterPro; IPR015404; Vps5_C.
DR   PANTHER; PTHR10555; SORTING NEXIN; 1.
DR   PANTHER; PTHR10555:SF31; SORTING NEXIN-2; 1.
DR   Pfam; PF00787; PX; 1.
DR   Pfam; PF09325; Vps5; 1.
DR   SMART; SM00312; PX; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
DR   PROSITE; PS50195; PX; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW   Transport {ECO:0000256|ARBA:ARBA00022927}.
FT   DOMAIN          131..260
FT                   /note="PX"
FT                   /evidence="ECO:0000259|PROSITE:PS50195"
FT   REGION          1..80
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          431..465
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        40..54
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   514 AA;  58275 MW;  6F578267A9355646 CRC64;
     MADTVRDPPP DGTDFHELED GEELFPEPAA APEESQPASL PAEDISTNSN GPKQDLLFDD
     DPEDLFAEAT EEVSLDSPER DVLLSDGPSP AITPITPPTS VITPRIGHAH DDMFTHSSFD
     EIEEEEGGDS FDIHISVSDP EKVGDGMNAY MAYKVSTKTS MLLFKQKDFS VKRRFSDFLG
     LHSKLASKYL HVGYIVPPAP EKSIVGMTKV KVGKEDQSSN EFVEKRRSAL ERYLMRTVKH
     PILLKDPDVL QFLESSELPR AVSTQALSSA GLLRMVNKAA DAVNKMTIKM NESDAWFEEK
     QQHFENLDVQ LRKLHASVES LVCHRKELSV NTAQFAKSAA MLGNSEDHTA LSRALSQLAE
     VEEKIDQLHQ DQANGDFYLF SELLGDYVRL LTAVKGVFEH RMKTWQKWQD SQMLLQKKRE
     AEAKLQFTNK PDKLQQAKDE IKEEIEELEG KVQQGERDFE QISKTIRKEV SRFEKERVRD
     FKMIIVKYLE SLVLTQQQLI KYWEAFLPEA KAIS
//