ID   A0A3Q1E9Z4_9TELE        Unreviewed;       734 AA.
AC   A0A3Q1E9Z4;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Spondin-1 {ECO:0000256|ARBA:ARBA00019594};
DE   AltName: Full=F-spondin {ECO:0000256|ARBA:ARBA00030964};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000000716.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000000716.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC       matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR   AlphaFoldDB; A0A3Q1E9Z4; -.
DR   STRING; 80966.ENSAPOP00000000716; -.
DR   Ensembl; ENSAPOT00000016395.1; ENSAPOP00000000716.1; ENSAPOG00000001950.1.
DR   GeneTree; ENSGT00940000154910; -.
DR   InParanoid; A0A3Q1E9Z4; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   CDD; cd08544; Reeler; 1.
DR   Gene3D; 2.60.40.2130; F-spondin domain; 1.
DR   Gene3D; 2.60.40.4060; Reeler domain; 1.
DR   Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 6.
DR   InterPro; IPR002861; Reeler_dom.
DR   InterPro; IPR042307; Reeler_sf.
DR   InterPro; IPR009465; Spondin_N.
DR   InterPro; IPR038678; Spondin_N_sf.
DR   InterPro; IPR000884; TSP1_rpt.
DR   InterPro; IPR036383; TSP1_rpt_sf.
DR   InterPro; IPR044004; TSP1_spondin_dom.
DR   NCBIfam; NF038123; NF038123_dom; 1.
DR   PANTHER; PTHR11311; SPONDIN; 1.
DR   PANTHER; PTHR11311:SF16; SPONDIN-1; 1.
DR   Pfam; PF02014; Reeler; 1.
DR   Pfam; PF06468; Spond_N; 1.
DR   Pfam; PF19028; TSP1_spondin; 1.
DR   Pfam; PF00090; TSP_1; 5.
DR   SMART; SM00209; TSP1; 6.
DR   SUPFAM; SSF82895; TSP-1 type 1 repeat; 6.
DR   PROSITE; PS51019; REELIN; 1.
DR   PROSITE; PS51020; SPONDIN; 1.
DR   PROSITE; PS50092; TSP1; 6.
PE   4: Predicted;
KW   Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT   DOMAIN          1..130
FT                   /note="Reelin"
FT                   /evidence="ECO:0000259|PROSITE:PS51019"
FT   DOMAIN          125..318
FT                   /note="Spondin"
FT                   /evidence="ECO:0000259|PROSITE:PS51020"
FT   REGION          288..323
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          648..681
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        293..307
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        650..673
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   734 AA;  82219 MW;  8D1E7229F0C7A150 CRC64;
     GKSPFKGDKS GPSSMDEGRT LIIEVTADDS ENFFQVWLIF LIKFFFLFGF QIVDEDDTQF
     MTNCPPAVTE STPRRRTRIQ VLWTAPPTGS GCVILKASIV QKRIIYFQDE GSLTIRLCEK
     ATEAPAIECC ACGTAKYRLT FYGNWSEKVH PKDYPRRANH WSALIGASHS RGYVLWEYGG
     YASEGVRQVA EFGSPIKMEE EIRQKGDEVL TVIKTKAQWP AWQPLNLRAA PSAEFSVDRT
     RHLMSFLTML GPSPDWNVGL SGEDLCTKDC GWVQRLVTDL IPWDAGTDGG VTYESPNKPT
     NPQEKIRPLT SLDHPQSPFY DPEGGAITPV AKVVVERIAR KGEQCNVVPD TIDDIVADIG
     QEEKEEDDTP ETCIYSGWSP WSACSSATCE KGRRMRQRML KAQLDLSVPC PHTQDFQPCM
     GPGCSMEEPS TCMMSEWISW SACSASCGMG MRSRERYVKQ YPEDGSLCQL NTEETEKCVV
     NEECSPSSCV VTEWAEWDPC SVTCGIGMKR RERMVKMPPI DGSMCKTEVA EVEKCMMPEC
     HTIPCMLSPW SDWSDCSVTC GRGVRTRQRM LKSDPAECTE ELEQTEKCML PECPVDCMVS
     EWSEWSECNK SCGKGHTIRT RMVKLEPQFG GSACPETIQR KKCKIRKCRP KTKEERGGGG
     GNRRRRGKQG RDSAVEEQPA GCRMQPWSSW TDCTKHCGGG IQERFMTAKK RAKGSGTAGC
     KDRKEIRACN VHPC
//