ID   A0A3Q1EH27_9TELE        Unreviewed;       445 AA.
AC   A0A3Q1EH27;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Chordin like 2 {ECO:0000313|Ensembl:ENSAPOP00000003766.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000003766.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000003766.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR   AlphaFoldDB; A0A3Q1EH27; -.
DR   STRING; 80966.ENSAPOP00000003766; -.
DR   Ensembl; ENSAPOT00000011196.1; ENSAPOP00000003766.1; ENSAPOG00000005282.1.
DR   GeneTree; ENSGT00940000166571; -.
DR   InParanoid; A0A3Q1EH27; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   Gene3D; 6.20.200.20; -; 1.
DR   Gene3D; 2.10.70.10; Complement Module, domain 1; 2.
DR   InterPro; IPR045717; CHRDL1/2.
DR   InterPro; IPR045716; CHRDL_1/2_C.
DR   InterPro; IPR001007; VWF_dom.
DR   PANTHER; PTHR46303:SF3; CHORDIN-LIKE PROTEIN 2; 1.
DR   PANTHER; PTHR46303; VWFC DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF19548; CHRDL_1_2_C; 1.
DR   Pfam; PF00093; VWC; 3.
DR   SMART; SM00214; VWC; 3.
DR   SUPFAM; SSF57603; FnI-like domain; 3.
DR   PROSITE; PS01208; VWFC_1; 2.
DR   PROSITE; PS50184; VWFC_2; 3.
PE   4: Predicted;
KW   Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           17..445
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018643752"
FT   DOMAIN          27..92
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   DOMAIN          106..172
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   DOMAIN          249..312
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   REGION          196..225
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   445 AA;  49513 MW;  737F6F1DC63C04D9 CRC64;
     MKSTFFFFSI IWFAAAELKP RKGSSGVVCT FKDKTYSPGD SWHPYLEPFG FMFCMRCVCT
     ETGHVKCNTI KCPTLPCENP VAEPQQCCPR CTDEPRIPAG LRASVKSCRY NGSIYQPGET
     FTKHDLFPFK QSNQCVMCTC SNGNIFCALK TCQPITCSSP VSVPDTCCLV CKDHGSSGSS
     STEDGNQQLN RGVRHSVDQC SGEQNRVRSD RATPPRVKTS PRGLSLSKLN LKGASETTVK
     ILLQRKHQRA CLYNGKTYSH GDMWHPVLGK VLECILCTCT DGLQDCKRIT CPSQYPCQHP
     MKSAGKCCKT CPESKAESNQ TQCYLGYKNN LLVYKVDSSL KVDSPNTVRI IAVERQSTAE
     VEVQVWNTVE GALQLMEIGD VQRKDIVDHP ENYTLLTTLD EETWKKFKDE GANLSKAPQT
     TICEDGIREM VTFLNPKQTE GQCSP
//