ID   A0A3Q1EIB3_9TELE        Unreviewed;       697 AA.
AC   A0A3Q1EIB3;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Ligand of Numb protein X 2-like {ECO:0000313|Ensembl:ENSAPOP00000004236.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000004236.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000004236.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   Ensembl; ENSAPOT00000010365.1; ENSAPOP00000023793.1; ENSAPOG00000005870.1.
DR   Ensembl; ENSAPOT00000010387.1; ENSAPOP00000004236.1; ENSAPOG00000005870.1.
DR   GeneTree; ENSGT00940000164372; -.
DR   OrthoDB; 3028121at2759; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd16780; mRING-HC-C3HC3D_LNX2; 1.
DR   CDD; cd00992; PDZ_signaling; 4.
DR   Gene3D; 2.30.42.10; -; 4.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR018957; Znf_C3HC4_RING-type.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR19964:SF41; LIGAND OF NUMB-PROTEIN X-LIKE PROTEIN; 1.
DR   PANTHER; PTHR19964; MULTIPLE PDZ DOMAIN PROTEIN; 1.
DR   Pfam; PF00595; PDZ; 4.
DR   Pfam; PF00097; zf-C3HC4; 1.
DR   SMART; SM00228; PDZ; 4.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 4.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS50106; PDZ; 4.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          50..88
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   DOMAIN          215..287
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          342..425
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          472..557
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          607..693
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   REGION          150..204
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          304..338
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          425..472
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        150..169
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        312..338
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        429..455
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   697 AA;  77291 MW;  202AF3CE90300589 CRC64;
     MATTETKVAG SGSTAGLSWA RVCKECGQQH EGLDSHLYEY QDEVDDELVC HICLQPLLRP
     MDTPCGHTYC FHCLSNFLKE QDFCPVDRQR LQLHQCRPSS LLVRNLLDKL TVMCPHSAEC
     QQQMQRCELQ PHLHNRCPVF RRLREEAEKR KRPSWNELKG RKGDGETSGD AKHSATQSRN
     HARDQPEPGL INPAYEESED DNTPLRSSLV AEASVVELFR DEPEEELGLR IVGGKDTPLG
     NIVIQEIVRD SLAARDGRLA PGDHILEVND VSLASVPHAR AITVLRQPAL LRLTVMQEKG
     FKLRDQRSDH HLSTPATSTA SQPSHSPHGN ATSNHNPGTV LQVTLMKSQR TEPLGIKLIR
     KSDESGVFIL DLLSGGLAAK DGKLRNNDKV LAINGHDLRH GTPESAAQII QGSEVRVNFV
     VMRPAEAQEE GGSSRDGQHS RASRRAPEPQ YFRRRSTYMK DPPGGFSSQE KTVSLKKEPR
     LSLGITIAGG RDCRSRLPVY ITSVQPVGCL HRDGTIKRGD VLLSINGVDL TQLTYNEAVS
     VLKAQTAQSQ VVLRVIQTLS EDSEDDAEAS SKDELDFMDD PRDDALNWTP LWTRWLGLPS
     HMHWCRDIVL QKTNNESWGF SIVGGYEESH GQQPFFIKTI VPGTPAHFDG RLKCGDEIVA
     VNGATTVGMN NSSLIPMLKL QKNKVTLTVV SWPGSLV
//