ID A0A3Q1EJ53_9TELE Unreviewed; 616 AA.
AC A0A3Q1EJ53;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Heterogeneous nuclear ribonucleoprotein U-like protein 2 {ECO:0000313|Ensembl:ENSAPOP00000003589.1};
OS Acanthochromis polyacanthus (spiny chromis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Acanthochromis.
OX NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000003589.1, ECO:0000313|Proteomes:UP000257200};
RN [1] {ECO:0000313|Ensembl:ENSAPOP00000003589.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A3Q1EJ53; -.
DR Ensembl; ENSAPOT00000011495.1; ENSAPOP00000003589.1; ENSAPOG00000005128.1.
DR GeneTree; ENSGT00940000160376; -.
DR Proteomes; UP000257200; Unplaced.
DR CDD; cd12884; SPRY_hnRNP; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR035778; SPRY_hnRNP_U.
DR PANTHER; PTHR12381; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER; 1.
DR PANTHER; PTHR12381:SF66; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U-LIKE PROTEIN 2; 1.
DR Pfam; PF13671; AAA_33; 1.
DR Pfam; PF02037; SAP; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00513; SAP; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50800; SAP; 1.
PE 4: Predicted;
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000257200}.
FT DOMAIN 6..40
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT DOMAIN 158..356
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 39..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 156..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 560..588
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 52..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..577
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 616 AA; 68548 MW; DE71667C492F1554 CRC64;
MKLTDIKKLK VAELRSRLKE LGLDSRGLKA ELVDRLWSAT EAGPGGTDDG EQMTLQPDSS
PTQQVLTPSS SPPTEAGVPA PCEADHGREL RDTGTQTEAE PGPPAVHPGS ECAPGAVTVC
QAETGEPGPG EDRGALLVED LDRGRSFYEF KEEIRYKRAK SPQPPLEREE AEEQDEDKVR
LDQHGGHLHF EVGPDGSCGQ PRFWSRFPLL WSGCRLTHGV QRGRVGFEAR LERRLLNTQP
EDHDVREPYG LRVGWSVAQS SLLLGEDELS FAYDGRGKKV SCGKEQEFGE PFSEGDIIGC
YAVNGAVELS FQRNGRFLGV AFTLDASVLL GCALFPHILC KSCSVRLLLD PTAPPWYPGP
PGFTLLAALP ADQRVRCTSA PSCRAQCEVV LLVGLPGSGK TFWARTHMKQ HPEKWYKLLG
TEELLACMIV SPTSRLRQAS QCLTDLIKVA AETPANYILD QCNILFSACR HKLQLFAGFR
RRVVVVFPSA DEWKRRLSQH QMTDGEHIPE TALLKLCSLP EQPADLLEEL QYVELPQHQA
QTVLLQYKDE ARRLLPPVHK QDKKKPRLYK KRPHPHCPPA PHRTEWSGFN GEKRQTLRYR
HHSDCTGSGL VTTILL
//
