ID A0A3Q1EMW3_9TELE Unreviewed; 359 AA.
AC A0A3Q1EMW3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Guanine nucleotide-binding protein G(q) subunit alpha {ECO:0000256|ARBA:ARBA00040847};
DE AltName: Full=Guanine nucleotide-binding protein alpha-q {ECO:0000256|ARBA:ARBA00042116};
OS Acanthochromis polyacanthus (spiny chromis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Acanthochromis.
OX NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000005124.1, ECO:0000313|Proteomes:UP000257200};
RN [1] {ECO:0000313|Ensembl:ENSAPOP00000005124.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004193};
CC Lipid-anchor {ECO:0000256|ARBA:ARBA00004193}. Golgi apparatus
CC {ECO:0000256|ARBA:ARBA00004555}. Nucleus membrane
CC {ECO:0000256|ARBA:ARBA00004126}.
CC -!- SIMILARITY: Belongs to the G-alpha family. G(q) subfamily.
CC {ECO:0000256|ARBA:ARBA00007976}.
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DR AlphaFoldDB; A0A3Q1EMW3; -.
DR STRING; 80966.ENSAPOP00000005124; -.
DR Ensembl; ENSAPOT00000008877.1; ENSAPOP00000005124.1; ENSAPOG00000006795.1.
DR GeneTree; ENSGT00940000161347; -.
DR InParanoid; A0A3Q1EMW3; -.
DR OrthoDB; 2897309at2759; -.
DR Proteomes; UP000257200; Unplaced.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0001664; F:G protein-coupled receptor binding; IEA:InterPro.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000654; Gprotein_alpha_Q.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF316; GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR PRINTS; PR00442; GPROTEINAQ.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
SQ SEQUENCE 359 AA; 41760 MW; CBBF9FD0D28E230A CRC64;
MTLSSVGACC LSPEAKEARR INDEIERQLR RDKRRSSREY KLLLLGTGES GKSTFIKQMR
IIHGRGYSDE DKRGFTRLVY QNIFTAMQAM IQAMNALQIP YKYEHNKANA SIVNKVDVEK
VTTLKKPYAD ALKSLWSDPG IQECYNRKRE YQLSDSAKYY LNDLDRIAEA AYLPSQQDVL
RVRVPTTGII EYPFDLESVV FRMVDVGGQR SERRKWIHCF ENVTSIMFLV ALSEYDQVLI
ESANENRMEE SMALFKTIIT YEWFEKSSII LFLNKIDLLE EKIMHSHLVD YFPEYDGPQQ
DVEAGKDFIL DMFVSLNPIK KKIIYSHFTC ATDTDNIRFV FCAVKDHILH TNLDIFNLV
//
