ID A0A3Q1ENV4_9TELE Unreviewed; 1132 AA.
AC A0A3Q1ENV4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Elongation factor like GTPase 1 {ECO:0000313|Ensembl:ENSAPOP00000005147.1};
GN Name=EFL1 {ECO:0000313|Ensembl:ENSAPOP00000005147.1};
OS Acanthochromis polyacanthus (spiny chromis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Acanthochromis.
OX NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000005147.1, ECO:0000313|Proteomes:UP000257200};
RN [1] {ECO:0000313|Ensembl:ENSAPOP00000005147.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3Q1ENV4; -.
DR STRING; 80966.ENSAPOP00000005147; -.
DR Ensembl; ENSAPOT00000008835.1; ENSAPOP00000005147.1; ENSAPOG00000000188.1.
DR GeneTree; ENSGT00550000074806; -.
DR InParanoid; A0A3Q1ENV4; -.
DR OrthoDB; 166721at2759; -.
DR Proteomes; UP000257200; Unplaced.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd01681; aeEF2_snRNP_like_IV; 1.
DR CDD; cd04096; eEF2_snRNP_like_C; 1.
DR CDD; cd01885; EF2; 1.
DR CDD; cd16268; EF2_II; 1.
DR CDD; cd16261; EF2_snRNP_III; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 3.90.1430.10; Yeast translation eEF2 (G' domain); 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF3; ELONGATION FACTOR-LIKE GTPASE 1; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000257200}.
FT DOMAIN 17..368
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 450..480
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 931..962
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..471
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1132 AA; 125509 MW; E70127126AC4D8F7 CRC64;
MGHTSLEKII ALQKNPANIR NLCILAHVDH GKTTLADCLV ASNGIISSRL AGKLRYLDSR
EDEQVRGITM KSSAISLHYR NGDQEYLLNL IDSPGHVDFS SEVSTAVRLC DGAIVVVDAV
EGVCPQTQAV LRQAWLENIR PVLVINKIDR LIMELQLTSQ EAYTHLQKIL GQVNAITGTL
FTSKVLEERA EKEKGEEKES ETLSGDQVFD WSAGLEEVDD SHLYFSPDQG NVVFASAIDG
WGFSIQQFAH IYSQRMGIKA GVLLKTLWGD FYLNAKAKKI MKGAQAKGKK PLFVQFVLDN
IWSLYDAVVT RRDREKVEKV VASLGIKVMA RDLRHSDPKV LLSAICSQWL PVSQAVLSMV
CEKLPSPLDM ASERAEKLMS VGARRFDSLP GQTQKLKTAF LQCSSEENAP VIVFVSKMFA
VDTKALPQHK PRPLTQEEIV QRRELARQRH ADRMAADQTA AESHKELAHS ESMSQESQPA
GLNTAMMESL TVKDSKPEEE EELKEIFIAF ARVYSGVVKK GQRVFVLGPK YDPALGLSMV
PEGCNASDCV SEVPHLSCCS MESLYLLMGR ELEELEEVPA GNVLGIGGLE ECVLKSATLS
STPACPPFTP LNFEATPIVR VAVEPKHPSE MPKLVRGMRL LNQADPCAEV LIQETGEHVL
VTAGEVHLQR CLDDLRDRFA KIEISASKPI IPFRETVVRP PKVDMVNEEL GKQQKVAIIH
QVKEEPSQGR SSDTLLVDPS GLVTLTTPSR LATVCVRAIP LPQEVTQLLE SNSEVIRTLE
QINMSLREGK SLDISLRTLE AIAGLKDQLD SLLQGRKWRN AVERIWAFGP RRYGPNILLN
NVESYQRPSV WQCLGRGDKT GEAGSQAAVL RDFDNSIISG FLLATLSGPM CEEPLMGVCF
CVERWDVQSL APAQHQESFD EDSISHKALA DNEVERSSEI SAQTEDMEAG LSQAGRRPEP
ASADCYGPVS GQLIAAMKEA CRHAFQTQPQ RLMAAMYTCE IMATAEVLGR VYGVLGKREG
RVLHEEMKEG TDMFIIKAVL PVAESFGFAD EIRKRTSGLA SPQLVFSHWE VISSDPYWVP
TTEEEYLHFG EKADSANQAL KYMNAVRRRK GLYVEEKIVE HAEKQRTLSK NK
//
