ID   A0A3Q1EUD7_9TELE        Unreviewed;       951 AA.
AC   A0A3Q1EUD7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Amyloid beta A4 precursor protein-binding family A member 2-like {ECO:0000313|Ensembl:ENSAPOP00000008746.1};
GN   Name=APBA2 {ECO:0000313|Ensembl:ENSAPOP00000008746.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000008746.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000008746.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3Q1EUD7; -.
DR   STRING; 80966.ENSAPOP00000008746; -.
DR   Ensembl; ENSAPOT00000002717.1; ENSAPOP00000008746.1; ENSAPOG00000010972.1.
DR   GeneTree; ENSGT00940000158943; -.
DR   InParanoid; A0A3Q1EUD7; -.
DR   OrthoDB; 2881953at2759; -.
DR   Proteomes; UP000257200; Unplaced.
DR   CDD; cd00992; PDZ_signaling; 2.
DR   CDD; cd01208; PTB_X11; 1.
DR   Gene3D; 2.30.42.10; -; 2.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR006020; PTB/PI_dom.
DR   PANTHER; PTHR12345:SF12; AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 2; 1.
DR   PANTHER; PTHR12345; SYNTENIN RELATED; 1.
DR   Pfam; PF00595; PDZ; 2.
DR   Pfam; PF00640; PID; 1.
DR   SMART; SM00228; PDZ; 2.
DR   SMART; SM00462; PTB; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 2.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50106; PDZ; 2.
DR   PROSITE; PS01179; PID; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          570..757
FT                   /note="PID"
FT                   /evidence="ECO:0000259|PROSITE:PS01179"
FT   DOMAIN          770..855
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          861..937
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   REGION          1..170
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          185..298
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          320..403
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          436..549
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        49..63
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        77..106
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        114..144
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        151..170
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        190..213
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        226..269
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        270..298
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        341..357
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        358..378
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        436..452
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        470..485
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        497..513
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        514..548
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   951 AA;  106453 MW;  72BD39DE79C470CB CRC64;
     MACKPPIMAQ RKRPGTSGGN SMAAPGPASC PTPHPTESCD LKALPARQRP LRYPKESHDS
     KPHSCKAQYS SPKNQDVGRS HHPDHHPEAE VDAEVEVKRY SSQADAELED QRPATPSTPE
     HNHDQDDHDD HDQPDFHGGA DSLDDDSSSE YINNTSDEEE DYDDGLAEED EGVTYYIRYC
     PEDDSYLEGM DCSSQGNCNH SHSHGQGDCT STMQLGGAHD DECQEAVEGW TEEGEGEVRE
     EEWVEDEEGE GEGREEWREE EEEVREEWRE GDEEGQQEWR QEDQVRQEQW AGRERHRVEE
     WGEGEGEVRC EVVEQDPDEQ IYNGRPEPIL DHHHHLHHHH QPAMQDNLHA RRADREEEEE
     AESEEYCPNE EEEEEGDEEE RHGRAYTGDY YAPEDNGNSV RVSPYRSRKV LVVEGETGEE
     AEEDIDQIVA EIKMSMSMGS LSSGTDQSPE ELAQDPAPSD YPHSKPDAAP YPPAHHRHDS
     RPKSLNLPSI HHNNPELQRG IKVHPRSPED RQRWPQEQVS NGAEQPRKQQ RSDLNVPLEN
     NNVPEPTKKV ASFPSFVDVP GPCEPEDLID GIIFAANYLG STQLLSERNP SKNIRMMQAQ
     EAVSRVKRVQ KAAKIKKKAS ADGDAQTLTE VDLFISTQRI KVLNADSQET MMDNALRTIS
     YIADIGNIVV LMARRRMPRT ASQDCIETTP GAPEAKKQYK MICHVFESED AQLIAQSIGQ
     AFSVAYQEFL RANGINPEDL SQKEYSDIIN TQEMYNDDLI HFSNSENCKE LQLEKSKGEI
     LGVVIVESGW GSILPTVILA NMMNGGPAAR SGKLSIGDQI MSINNTSLVG LPLATCQGII
     KGLKNQVQVK MNIVSCPPVT TVLIKRPDLK YQLGFSVQNG IICSLMRGGI AERGGVRVGH
     RIIEINGQSV VATAHEKIVQ ALSNSVGEIH MKTMPAAMFR LLTGQETPMY I
//