ID   A0A3Q1EUP4_9TELE        Unreviewed;       652 AA.
AC   A0A3Q1EUP4;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=DAB2 interacting protein {ECO:0000313|Ensembl:ENSAPOP00000007452.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000007452.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000007452.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   Ensembl; ENSAPOT00000004920.1; ENSAPOP00000007452.1; ENSAPOG00000009510.1.
DR   GeneTree; ENSGT00940000155853; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   CDD; cd04013; C2_SynGAP_like; 1.
DR   CDD; cd05136; RasGAP_DAB2IP; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR021887; DAB2P_C.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR039360; Ras_GTPase.
DR   InterPro; IPR023152; RasGAP_CS.
DR   InterPro; IPR001936; RasGAP_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   PANTHER; PTHR10194:SF26; DISABLED HOMOLOG 2-INTERACTING PROTEIN; 1.
DR   PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR   Pfam; PF00168; C2; 1.
DR   Pfam; PF12004; DAB2P_C; 1.
DR   Pfam; PF00616; RasGAP; 1.
DR   SMART; SM00239; C2; 1.
DR   SMART; SM00323; RasGAP; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50004; C2; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR   PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200}.
FT   DOMAIN          1..108
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          99..217
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   DOMAIN          277..471
FT                   /note="Ras-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50018"
FT   REGION          539..560
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   652 AA;  73870 MW;  AA9103DEA5FBAD2B CRC64;
     NKNTIALKIK IKLKKKXTHT HTHTHTHTHT HTHTHTCSID SESLLSAGCV SSLELTMDQS
     VIIKPVHSSL LGQDYCFEVT TSTGTKCFSC RSAAERDKWM ENLRRAVHPN KDNSRRLENV
     LTVWVIEAKD LPAKKRYFCE LCLDDSLYAR TSCKLRTDNV FWGERFDFSS LPSVSSVTLH
     LYKDTDRKRK KDKSSYVGLV NIPVATVTGR QLVEKWYSVS TPSTSRGKSS VPTVRVKARY
     QSIVILPMEQ YKEFAEYISS NYLLLCSTLE ASISLRAKEE LAAALVHILH STGKAKDFLT
     DLMMSEVDRC RDNDQLIFRE NTLATKSIEE YLKLIGQKYL QDALGTAETH LTHTSSDENC
     EVDPSRCSTS DLLEHQANLR MCCELAFCKI LDSYRVFPRE LKEVFASWRQ ECGNRGRPDI
     SERLISASLF LRFLCPAVMS PSLFDLMQEY PDERTARTLT LIAKVIQNLA NFSKFGTKEE
     YMLFMNDFVE RQWSSMQRFL QEISNPDGLN HTAGFDGYID LGRELSSLHT LLTELDQVTH
     PTEQVAHPTE QVAHPTEQVT ASSSSSAGTR LSAHLSVCMS TYLSVCSPVC QYEYLCLTCY
     LCRLMAVEEE LKKDHSDMQA VVDSKQKIIE AQVPVCLHTC VSLFSVSPVC LT
//