ID A0A3Q1EWL7_9TELE Unreviewed; 463 AA.
AC A0A3Q1EWL7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Forkhead box A3 {ECO:0000313|Ensembl:ENSAPOP00000008504.1};
OS Acanthochromis polyacanthus (spiny chromis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Acanthochromis.
OX NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000008504.1, ECO:0000313|Proteomes:UP000257200};
RN [1] {ECO:0000313|Ensembl:ENSAPOP00000008504.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR AlphaFoldDB; A0A3Q1EWL7; -.
DR STRING; 80966.ENSAPOP00000008504; -.
DR Ensembl; ENSAPOT00000003163.1; ENSAPOP00000008504.1; ENSAPOG00000010624.1.
DR GeneTree; ENSGT00940000166203; -.
DR InParanoid; A0A3Q1EWL7; -.
DR Proteomes; UP000257200; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0019904; F:protein domain specific binding; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR013638; Fork-head_N.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR018533; Forkhead_box_C.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR PANTHER; PTHR11829:SF201; HEPATOCYTE NUCLEAR FACTOR 3-GAMMA; 1.
DR Pfam; PF00250; Forkhead; 1.
DR Pfam; PF08430; Forkhead_N; 1.
DR Pfam; PF09354; HNF_C; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000257200}.
FT DOMAIN 151..245
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 151..245
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 123..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 252..355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 285..306
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 313..355
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 463 AA; 49835 MW; 9B162A73B1DD7492 CRC64;
FRLTSPCEIH DFCPHTESFI MYSSPSTMNS GLGSMGSMGT INSYINLNPA TASPAGMNMA
YPSSSLSSSP LASMGPGPGH MSLSPVASSL SSGSLTQLGS AAPGPLGSLS HYQNMGQSMG
QLGYAPSATL NRAGPKEMPP KPYRRSLTHA KPPYSYISLI TMAIQQSGSK MLTLNEIYQW
IMDLFPYYRE NQQRWQNSIR HSLSFNDCFV KVARSPDKPG KGSYWTLHPQ SGNMFENGCY
LRRQKRFKIE DKMAKKAGKS QEGSSGKGGH SEHLVEDRSP TGGSEGADSA HSDNSHPGSS
DDQPHPRNTL VPLDCPSLSS SHLHSPPVSL PPSSSTSSSI PPSSLSLSGA SSVSNPLLHS
QSLASSSHLL PSTMQQHMDL QSDALKSLDP HYNFNHPFSI TNLMSNEQKM DLKSYQDQVM
AYNSYTSGSP VGAKQIYDSP GPAAMDSGAY YQTLYSRSVL NAS
//
