ID   A0A3Q1EX73_9TELE        Unreviewed;       719 AA.
AC   A0A3Q1EX73;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Exostosin glycosyltransferase 2 {ECO:0000313|Ensembl:ENSAPOP00000009008.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000009008.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000009008.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004648}; Single-pass type II membrane protein
CC       {ECO:0000256|ARBA:ARBA00004648}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 47 family.
CC       {ECO:0000256|ARBA:ARBA00010271}.
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DR   AlphaFoldDB; A0A3Q1EX73; -.
DR   STRING; 80966.ENSAPOP00000009008; -.
DR   Ensembl; ENSAPOT00000002284.1; ENSAPOP00000009008.1; ENSAPOG00000011289.1.
DR   GeneTree; ENSGT00940000156620; -.
DR   InParanoid; A0A3Q1EX73; -.
DR   OrthoDB; 1220028at2759; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR   GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR   InterPro; IPR004263; Exostosin.
DR   InterPro; IPR040911; Exostosin_GT47.
DR   InterPro; IPR015338; GT64.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR48261; ACETYLGLUCOSAMINYLTRANSFERASE; 1.
DR   PANTHER; PTHR48261:SF2; EXOSTOSIN-1-LIKE; 1.
DR   Pfam; PF03016; Exostosin; 1.
DR   Pfam; PF09258; Glyco_transf_64; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        24..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          101..381
FT                   /note="Exostosin GT47"
FT                   /evidence="ECO:0000259|Pfam:PF03016"
FT   DOMAIN          457..702
FT                   /note="Glycosyl transferase 64"
FT                   /evidence="ECO:0000259|Pfam:PF09258"
FT   COILED          256..283
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   719 AA;  82295 MW;  A1655FCF190BBF8E CRC64;
     MYTSGKYSSR GPALIPRMKT KHRIYYITLF SVVLLGLIAT GMFQFWPHSI ESTADWTLDK
     RSVHDAPLIR LPVSSPIPER GDLSCRMHTC FDVYRCGYNP KNRIKVYIYP LQRFVDELGV
     PISSTGLSRE YNDLLSAISD SDFYTDDVTR ACLFIPSIDV LNQNSLRIRE TAQALAMLPR
     WDKGMNHLLF NMLPGGPPDY NTALDVPRDR ALLAGGGFST WTYRQGYDVS IPVYSPLSAD
     VELPEKQPGP RRYFILSSQT AIHREYRAEL ERLKEENGEA LLLLDKCSNL SQGAASARKR
     CYKGQVYDYP QILQESSFCV VLRGARLGQA ALSDVLQAGC VPVILADSYI LPFSEVLDWK
     RASVVIPEEK LSEMYTILKS IPHRQVEEMQ RQARWFWEAY FSSMKAIGLT TLQIINDRIY
     PYAARSYEQW NNPPVVKWSS VNSPLFLPLI PPRAPGFTAV VLTYDRVESL FRVITEISKV
     PSLAKLLVVW NNQNKSPPEE SLWPKIGVPL KVVRTKENKL SNRFFPYDEI ETEAVLAIDD
     DIIMLTSDEL QFGYEVWREF PDRLVGYPGR LHLWDHEMGK WKYESEWTNE VSMVLTGAAF
     YHKYFNYLYT YKMPGDIKNW VDAHMNCEDI AMNFLVANIT GKAPIKVTPR KKFKCPECTA
     IDGLSLDQTH MVERSECINK FASVFGTMPL KVVEHRADPV LYKDDFPEKL KSFPNIGSL
//