ID   A0A3Q1EXG0_9TELE        Unreviewed;       662 AA.
AC   A0A3Q1EXG0;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Sorbin and SH3 domain containing 2 {ECO:0000313|Ensembl:ENSAPOP00000009926.1};
GN   Name=SORBS2 {ECO:0000313|Ensembl:ENSAPOP00000009926.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000009926.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000009926.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q1EXG0; -.
DR   Ensembl; ENSAPOT00000000723.1; ENSAPOP00000009926.1; ENSAPOG00000012334.1.
DR   GeneTree; ENSGT00940000157056; -.
DR   Proteomes; UP000257200; Unplaced.
DR   Gene3D; 2.30.30.40; SH3 Domains; 3.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   InterPro; IPR003127; SoHo_dom.
DR   PANTHER; PTHR14167:SF56; DREBRIN-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR   Pfam; PF00018; SH3_1; 2.
DR   Pfam; PF14604; SH3_9; 1.
DR   Pfam; PF02208; Sorb; 1.
DR   PRINTS; PR00499; P67PHOX.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00326; SH3; 3.
DR   SMART; SM00459; Sorb; 1.
DR   SUPFAM; SSF50044; SH3-domain; 3.
DR   PROSITE; PS50002; SH3; 3.
DR   PROSITE; PS50831; SOHO; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          162..224
FT                   /note="SoHo"
FT                   /evidence="ECO:0000259|PROSITE:PS50831"
FT   DOMAIN          431..490
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          506..567
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          603..662
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          17..150
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          227..436
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          570..591
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..68
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        76..101
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        116..150
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        246..262
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        264..279
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        287..315
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        346..360
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        361..376
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        390..422
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   662 AA;  73199 MW;  5DB186DE2F168C4A CRC64;
     MNTDSGGCVR KSVALSLKLS PMKRVQSSPN LATGSDSHSS DLDSWRSRSA TDGLKNGDAS
     SSSLAAKGFR SVRPNLQEKK SPTQGQVLSH AMNGSASHPQ RPLSPPSYPP PPASLHTGLQ
     RQSRSSEGSE AVTRESVVSG HTSVSSTVPI ARFSEEEKKV SVIKAPHYEG IGPVDESGIP
     IAIRTTVDRP KDWYKTMFKQ IHKVHKADDD YSDTYSAAYA VINNDDYSLS SGTTMAHPAP
     RTHTYRPLSK SPSDNGGHLG SQEPSPSPVP PPPPPMPSLL QLRANEKDST DMNEWGPPDR
     KVDTRKYRAE PKSIFEYEPG KSSILEQERP TSLHIAPADK PPERPASSAS DYRKRRKSEP
     SSSQVNAQSQ SRAATSPKPV DAYRPSSSLR KPVIRSSPSS PSRAKDQDVS RSYSTMDGRH
     TPQSRRPTPD REKQPARAIY DFKAQTAKEL TFKKGDAVNI IRQIDTNWYE GEHRGRVGIF
     PISYVEKMPS TEKQQPVRPP PPAHVREIGE AVARYNFNAD TNVELSLRKG ERVIVIRQVD
     QNWYEGKIPD TTKQGIFPVS YVDIVKRSPS KSSTHHIDPH GYPGNRTPSS TPIKRLVQDA
     LHGGGDPYQA LYNYVPRNED ELELREGDIV DVMEKCDDGW FVGTSRRSKL FGTFPGNYVK
     QL
//