ID   A0A3Q1EXX5_9TELE        Unreviewed;       661 AA.
AC   A0A3Q1EXX5;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Voltage-dependent calcium channel alpha-1 subunit IQ domain-containing protein {ECO:0000259|SMART:SM01062};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000010116.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000010116.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3Q1EXX5; -.
DR   STRING; 80966.ENSAPOP00000010116; -.
DR   Ensembl; ENSAPOT00000000386.1; ENSAPOP00000010116.1; ENSAPOG00000012556.1.
DR   GeneTree; ENSGT00940000155275; -.
DR   InParanoid; A0A3Q1EXX5; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0034702; C:monoatomic ion channel complex; IEA:UniProtKB-KW.
DR   GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 1.
DR   Gene3D; 6.10.250.2180; -; 1.
DR   InterPro; IPR031649; GPHH_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR014873; VDCC_a1su_IQ.
DR   PANTHER; PTHR45628; VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1; 1.
DR   PANTHER; PTHR45628:SF6; VOLTAGE-DEPENDENT N-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1B; 1.
DR   Pfam; PF08763; Ca_chan_IQ; 1.
DR   Pfam; PF16905; GPHH; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   SMART; SM01062; Ca_chan_IQ; 1.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE   4: Predicted;
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW   Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT   TRANSMEM        80..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          237..271
FT                   /note="Voltage-dependent calcium channel alpha-1 subunit
FT                   IQ"
FT                   /evidence="ECO:0000259|SMART:SM01062"
FT   REGION          265..284
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          328..439
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          456..517
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          637..661
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        329..343
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        359..377
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        378..392
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        456..478
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        485..504
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   661 AA;  73996 MW;  D9C430206AB2D791 CRC64;
     MLFFIYAIIG MQVFGNIDLN DDTAINHHNN FRTFLQALML LFRSATGEAW HEIMLSCLSR
     RACDERSGTH GKECGSDFAY FYFVSFIFLC SFLMLNLFVA VIMDNFEYLT RDSSILGPHH
     LDEFIRVWAE YDPAACGRIK YLDMYQMLLH MSPPLGLGKK CPPRIAYKRL VKMNMPIADD
     NTVHFTSTLM ALIRTALEIK LASAQRLSDA ELKKELSTVW PSLSQKTMDL LVTPHKHNEL
     TVGKVYAALM IFDYYKQNLA RKQQQSASDS RVQHPHHTCL PDTHTDTHVH VQRLTHTLTG
     CSSANLHACS HIHDASFLSV LPQSVPDASP IKRSASTVTP QRPPEVNLRD YNLEKPSKDR
     PHHHHHHHHH HCHHRRDRDK DKDREKRQRS LDTPTVGHPS GSGAPGEPAS DPAASRERTH
     DRGRSHERKH HHSSTDKQRY YSCDRYSSRE HCLTKSATAS CAAPPSEGQE TVNKQIKGGF
     NGSEVPVALS SSSSTPSRGR RQLPQTPLTP RPGVAYKTAN SSPVHFVSSQ ASLSPGNLSR
     GLSEHNALRH SGSHHFPCPV TRINSEPFLG RGHSEALGSP YSSLQDQLDV FHDVASLSPS
     FRAGRSSQTA LPRMMGALLP APQQNLGVPN GYHFSFGDST SPGSGSRAPR YYQETEVDEW
     C
//