ID   A0A3Q1F041_9TELE        Unreviewed;       676 AA.
AC   A0A3Q1F041;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=TRMT1-like protein {ECO:0000256|ARBA:ARBA00015939};
GN   Name=TRMT1L {ECO:0000313|Ensembl:ENSAPOP00000009427.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000009427.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000009427.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: May play a role in motor coordination and exploratory
CC       behavior. {ECO:0000256|ARBA:ARBA00003652}.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. Trm1 family. {ECO:0000256|PROSITE-ProRule:PRU00958}.
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DR   AlphaFoldDB; A0A3Q1F041; -.
DR   STRING; 80966.ENSAPOP00000009427; -.
DR   Ensembl; ENSAPOT00000001574.1; ENSAPOP00000009427.1; ENSAPOG00000011807.1.
DR   GeneTree; ENSGT00530000063646; -.
DR   InParanoid; A0A3Q1F041; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0160102; F:tRNA (guanine(10)-N2)-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007610; P:behavior; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.56.70; N2,N2-dimethylguanosine tRNA methyltransferase, C-terminal domain; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR002905; Trm1.
DR   InterPro; IPR042296; tRNA_met_Trm1_C.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR10631; N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR10631:SF1; TRMT1-LIKE PROTEIN; 1.
DR   Pfam; PF02005; TRM; 2.
DR   SMART; SM00355; ZnF_C2H2; 2.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS51626; SAM_MT_TRM1; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE   3: Inferred from homology;
KW   Behavior {ECO:0000256|ARBA:ARBA00022610};
KW   Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW   ProRule:PRU00958}; Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU00958};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW   ECO:0000256|PROSITE-ProRule:PRU00958};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW   ProRule:PRU00958}; tRNA processing {ECO:0000256|PROSITE-ProRule:PRU00958};
KW   tRNA-binding {ECO:0000256|ARBA:ARBA00022555, ECO:0000256|PROSITE-
KW   ProRule:PRU00958}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT   DOMAIN          146..173
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   REGION          1..58
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..22
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   676 AA;  74954 MW;  1E03928133962B5B CRC64;
     MAELREADAA KPHREDVSIK LDNVEDAPST TYQAAEQVAE NEADGDSDTK PSTTASERHI
     SIQTKLKGLE MLADLDGAGR KSCPLCPEEK FKACYSHKLR RHLQNLHWKV YVELQGQRMC
     ICHLPCRNLK PSLSGDQVSG RHVAHYHCVV CSVTIARKTD MISHLKRHIN KGETEASYSG
     SSDVPFEEPA PSGHAYEIMK ELGTNVQLLP NHTTPQKSDT YFNRKMKSNR QLVFCSLAVL
     TEERNPLECL DAFGATGIMG LQWAKHLRNA IKVTITDISD TCVKMIKENC KLNHIRVDGC
     PRGPRGPDSE VEGVPIATVE VAKMDANVIL HLRAFDYIHL DPYGTAVNYL DAAFRNVRNL
     GIISVTSTDT SSLYAKSPNV TLRHYGCHIV RTEYYREVAA RMVVATVARA AGRCNKGIEV
     LLAVALEHFV LVVVRVLRGP TQADESAKKL RKLVHCQWCE ERLFLKQGNM VDDTLPCNCH
     GSLPGKTAVQ LGPLWSGPLF NTGFLRKMLS AAVQHSMDDI QPLVKTLICE SECTTLKSFV
     HGPSALTNQV ECGVVIKTLQ SGEELGPADQ SGKRKTGEES GSVVKKLKSD VSLEHPPFYY
     SIHRHSIRGM NMPKLNKFLQ YLTEAGFRVS RTHFDPTGVR TDATLLKFKS VLTKYSVPTY
     TNATATQKSV STETTT
//