ID   A0A3Q1F0M9_9TELE        Unreviewed;       343 AA.
AC   A0A3Q1F0M9;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=DNA repair protein {ECO:0000256|PIRNR:PIRNR005856};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000009954.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000009954.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: Involved in the homologous recombination repair (HRR) pathway
CC       of double-stranded DNA, thought to repair chromosomal fragmentation,
CC       translocations and deletions. {ECO:0000256|PIRNR:PIRNR005856}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR005856}.
CC       Cytoplasm {ECO:0000256|PIRNR:PIRNR005856}.
CC   -!- SIMILARITY: Belongs to the RecA family. RAD51 subfamily.
CC       {ECO:0000256|PIRNR:PIRNR005856}.
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DR   AlphaFoldDB; A0A3Q1F0M9; -.
DR   STRING; 80966.ENSAPOP00000009954; -.
DR   Ensembl; ENSAPOT00000000673.1; ENSAPOP00000009954.1; ENSAPOG00000012312.1.
DR   GeneTree; ENSGT00930000151053; -.
DR   InParanoid; A0A3Q1F0M9; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   CDD; cd19491; XRCC3; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR   InterPro; IPR016467; DNA_recomb/repair_RecA-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR020588; RecA_ATP-bd.
DR   InterPro; IPR047348; XRCC3-like_C.
DR   PANTHER; PTHR46487; DNA REPAIR PROTEIN XRCC3; 1.
DR   PANTHER; PTHR46487:SF1; DNA REPAIR PROTEIN XRCC3; 1.
DR   Pfam; PF08423; Rad51; 1.
DR   PIRSF; PIRSF005856; Rad51; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50162; RECA_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Cytoplasm {ECO:0000256|PIRNR:PIRNR005856};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleus {ECO:0000256|PIRNR:PIRNR005856};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200}.
FT   DOMAIN          78..259
FT                   /note="RecA family profile 1"
FT                   /evidence="ECO:0000259|PROSITE:PS50162"
SQ   SEQUENCE   343 AA;  37624 MW;  403BECBB34DD5974 CRC64;
     MNWDQLELSP RILAAVRRAK LKSVKEVLCL SSLDLQTLTG LSLSDVQQLL TAAATTCRRH
     PPVTALQLQR GECPSIESGL RLSVGCPVLD QLLRGGLPAG VITELSGESG AGKTQLALQL
     CLSVQYPKEH GGLNSGALYI CTEDSFPIKR LQQLIREQPS LRSDVPPSLI SSLHFSNNIY
     IEHTADLDSL QVCLSRRAPL LLAQGLVRLL VVDSVAALFR SEFQADDWLE RNRQLLTFSS
     ALHHLSQEFT TPVLCINQVT DVFNQSDNSL GPSSSSVSPA LGLAWANQVM VRLILRRLRE
     AVTRGDQSSI LRRLEVAFAP HLPRDGRDAA VWREGMRGVL NSD
//