ID   A0A3Q1F452_9TELE        Unreviewed;      1073 AA.
AC   A0A3Q1F452;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Nuclear export mediator factor {ECO:0000313|Ensembl:ENSAPOP00000011064.1};
GN   Name=NEMF {ECO:0000313|Ensembl:ENSAPOP00000011064.1};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000011064.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000011064.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the NEMF family.
CC       {ECO:0000256|ARBA:ARBA00008318}.
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DR   AlphaFoldDB; A0A3Q1F452; -.
DR   STRING; 80966.ENSAPOP00000011064; -.
DR   Ensembl; ENSAPOT00000031454.1; ENSAPOP00000011064.1; ENSAPOG00000013672.1.
DR   GeneTree; ENSGT00390000018516; -.
DR   InParanoid; A0A3Q1F452; -.
DR   OrthoDB; 129892at2759; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0072344; P:rescue of stalled ribosome; IEA:UniProt.
DR   Gene3D; 2.30.310.10; ibrinogen binding protein from staphylococcus aureus domain; 1.
DR   InterPro; IPR021846; NFACT-C.
DR   InterPro; IPR008532; NFACT_RNA-bd.
DR   PANTHER; PTHR15239; NUCLEAR EXPORT MEDIATOR FACTOR NEMF; 1.
DR   PANTHER; PTHR15239:SF6; RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF; 1.
DR   Pfam; PF11923; NFACT-C; 1.
DR   Pfam; PF05670; NFACT-R_1; 1.
DR   Pfam; PF05833; NFACT_N; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200}.
FT   DOMAIN          524..634
FT                   /note="NFACT RNA-binding"
FT                   /evidence="ECO:0000259|Pfam:PF05670"
FT   DOMAIN          972..1063
FT                   /note="NFACT protein C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11923"
FT   REGION          418..448
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          687..981
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          297..341
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          479..506
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        428..448
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        699..730
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        742..768
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        769..798
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        818..832
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        839..859
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        867..883
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        892..917
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        927..953
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        954..969
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1073 AA;  121113 MW;  CEC36383BE5E0C7E CRC64;
     MKTRFTTVDI RAVIAEINAN YIGMRVNNVY DIDNKTYLIR LQKPDSKAVL LIESGTRIHS
     TDFEWPKNMM PSGFAMKCRK HLKTRRLTQV KQLGIDRIVD IQFGSDEAAY HLIIELYDRG
     NIILADHEYT ILNLLRFRTA EAEDVKIAVR ERYPVENARP PEPLISLERL TEILSKAPNG
     EQVKRVLNPH LPYGASLIEH SLIEAGLPGF VKVDSQVDAA QVAPKILEAL QIAETYMEKT
     ENFSGKGYIL QKREKKPSLT PGKPSEELLT YDEFHPFLFA QHTQSPYLEF DTFDKAVDEF
     FSKMESQKID MKALQQEKQA LKKLENVKRD HEQRLEALHQ AQEVDRVKGE LVEMNLPVVE
     RALQVVRSAL ANQVDWTEIG IIVKEAQAAG DPVACAIKEL KLQTNHITML LKNPYISEED
     QEEEENKDTV EEKGKKNKNK DKGQNKKLQK NKPMLVDVDL GLSAYANAKK YYDFKRTAEK
     KEQKTIEAAD KAMKSAEKKT QQTLKEVQTV TTIQKARKVY WFEKFLWFIS SENYLVIAGR
     DQQQNEMIVK RYLRTGDIYV HADLHGATSC VIKNPSGDPI PPRTLTEAGT MAVCYSAAWD
     AKIITSAWWV HHHQVSKTAP TGEYLTTGSF MIRGKKNFLP PSYLIMGFGF LFKVDEQSVF
     RHRGERKVKT VEEDMEDVTS RTAELLEEGE ELIGDDSSNE DQGEEKTGDG ESKEVGEKIV
     KEDDAAHERT AANTGEMLSE QSNVEEEGHR EEDSDQEKEM KNDESEEFSF PDTTISLSHL
     QPSRSAQNPG FKKETTAQAE ADSQGKKHMT AKQRREEKKK KQKQEGCEAE EKTDIPFSGS
     AVDQGSKSGG GTSQAPLKRG QKNKLKKIKE KYKDQDEEDR ELMMQLLGSA GSTKEEKDKG
     KKGKKGKGKE EPIRKPASQK QQQKPRNVEA AVKKPEQTGG EEEERQPGEE GGPAEQEEKE
     DDVDQDNPGA EEAENLLTSL TGQPHSEDVL LFAVPVCAPY TALSNYKHKV KLTPGSQKKG
     KAARTAVLSF MKAKEVSTRE KDLLRSVKDS DLSRNMPGKV KVSAPNLLAA KKK
//