ID   A0A3Q1F4W2_9TELE        Unreviewed;      1127 AA.
AC   A0A3Q1F4W2;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Titin {ECO:0008006|Google:ProtNLM};
OS   Acanthochromis polyacanthus (spiny chromis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Acanthochromis.
OX   NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000011002.1, ECO:0000313|Proteomes:UP000257200};
RN   [1] {ECO:0000313|Ensembl:ENSAPOP00000011002.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q1F4W2; -.
DR   Ensembl; ENSAPOT00000031420.1; ENSAPOP00000011002.1; ENSAPOG00000013587.1.
DR   GeneTree; ENSGT01100000263523; -.
DR   Proteomes; UP000257200; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00063; FN3; 7.
DR   CDD; cd05748; Ig_Titin_like; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 12.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013098; Ig_I-set.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   PANTHER; PTHR14340; MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3; 1.
DR   PANTHER; PTHR14340:SF21; MYOSIN BINDING PROTEIN C2; 1.
DR   Pfam; PF00041; fn3; 7.
DR   Pfam; PF07679; I-set; 3.
DR   PRINTS; PR00014; FNTYPEIII.
DR   SMART; SM00060; FN3; 8.
DR   SMART; SM00409; IG; 4.
DR   SMART; SM00408; IGc2; 3.
DR   SUPFAM; SSF49265; Fibronectin type III; 6.
DR   SUPFAM; SSF48726; Immunoglobulin; 5.
DR   PROSITE; PS50853; FN3; 6.
DR   PROSITE; PS50835; IG_LIKE; 3.
PE   4: Predicted;
KW   Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW   Membrane {ECO:0000256|ARBA:ARBA00022989};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          1..82
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   DOMAIN          86..173
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          312..409
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   DOMAIN          409..495
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          504..597
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   DOMAIN          603..698
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   DOMAIN          701..797
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   DOMAIN          801..893
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          913..1006
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
SQ   SEQUENCE   1127 AA;  124038 MW;  0D2CAABFCCDE2D95 CRC64;
     MLRWTAPEYD GGSLITGYVV EKRDLPEGKW MKASFANVIE HEFTVTGLTE DSKYDFRIIA
     RNAAGAVSKP SETTGSITAK DEVDPPKCET DPMYNQTIVI SAGETFTLEA SMEGKPIPTA
     QWFKGDVEVE NSARAEIKNT DFKALLIVKD AIRVDGGQYM LVLTNVAGTK TVPFSVKVLD
     RPGPSEGPLT ADGTLNECAQ IEVTSSYTML VIENVDRFDT GKYVLTLENL SGSKSAFINV
     RVLDSPSAPT NLEVKDVKRN SVSLSWEPPL IDGGAKISHY IVEKREQKRM AFTSVCLPAS
     TDQVKVSEAP LPPGKIVLVD VTRHTVTLSW EKPDHDGGSK ITNYIVEMQP KGDDKWTVCS
     EVKALEATIE GLTTGEEYSF RVIAVNDKGR SDAKPLAASV VVKDITMEPI INLLFNTYSV
     KSGDDLKIDV PFKGRPQPEV SWKKDGQVLK QTTRVNVVTS KTSSKIVIKD ATKEDVGKYE
     ITLTNSVGTK TGEISVIILD KPGPPSNIKV DEVSADFICL SWDPPTYDGG CQINNYVVEK
     RDTTTTTWQI VSATVARTSI KVSRLTQGTE YQFRIAAENR YGKSHAVDSA PVVAQYPFEP
     PGSPTNLHVA HATKTGMLVV WGRPASDGGS PVIGYHVECK DQSSILWTKV NRGLLAETQF
     KMTGIEEGLQ YQFRVYAENI AGIGPCTKAS EPVAARDPCE PPHNLRVTNI TRTSVSLFWE
     KPEYDGGVKI TGYIVERKEL PNGRWLKCNF TNLQDTYFDV TGLTEDVQYD FHVIAKNSAE
     LLSVPSETTG PVTVKDDVDP PTIILEDKFR QLVVIKAGDI IRVDAEITGR PLPVVSWSKD
     GKEIEAKARC EITSTNFATT LIVRDAIRRD SGQYVLTLHN VYRVFAENAA GLSAPSIACP
     LTKAEDPQFL PSPPAKPKIV DSTKTTVTLS WNKPLFDGGA PVTGYRVEYR KTLDDEWIVG
     VQNTKNTEFT VVGLTPGAEY VFVVKSINKI GVSESSPESD KQVAKEREEE PIFDISNEMR
     KTLIVRDGSS FTMTVPFRGK PIPSVTWTKP DVDLRVRMKD RNSILWQRVN KMVIRATHFK
     VTNINAGLIY EFKVAAENAA GISAFSKVSD AVLAIDACGK WRIPVPM
//