ID A0A3Q1F8C9_9TELE Unreviewed; 849 AA.
AC A0A3Q1F8C9;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=protein-serine/threonine phosphatase {ECO:0000256|ARBA:ARBA00013081};
DE EC=3.1.3.16 {ECO:0000256|ARBA:ARBA00013081};
OS Acanthochromis polyacanthus (spiny chromis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Acanthochromis.
OX NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000014016.1, ECO:0000313|Proteomes:UP000257200};
RN [1] {ECO:0000313|Ensembl:ENSAPOP00000014016.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] +
CC phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:83421; EC=3.1.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001512};
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DR AlphaFoldDB; A0A3Q1F8C9; -.
DR STRING; 80966.ENSAPOP00000014016; -.
DR Ensembl; ENSAPOT00000022325.1; ENSAPOP00000014016.1; ENSAPOG00000016860.1.
DR GeneTree; ENSGT01040000240451; -.
DR InParanoid; A0A3Q1F8C9; -.
DR Proteomes; UP000257200; Unplaced.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0008420; F:RNA polymerase II CTD heptapeptide repeat phosphatase activity; IEA:InterPro.
DR CDD; cd07521; HAD_FCP1-like; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR011948; Dullard_phosphatase.
DR InterPro; IPR004274; FCP1_dom.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR040078; RNA_Pol_CTD_Phosphatase.
DR NCBIfam; TIGR02251; HIF-SF_euk; 1.
DR PANTHER; PTHR12210:SF139; CARBOXY-TERMINAL DOMAIN RNA POLYMERASE II POLYPEPTIDE A SMALL PHOSPHATASE 1; 1.
DR PANTHER; PTHR12210; DULLARD PROTEIN PHOSPHATASE; 1.
DR Pfam; PF03031; NIF; 1.
DR SFLD; SFLDG01124; C0.1:_RNA_Pol_CTD_Phosphatase; 1.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SMART; SM00577; CPDc; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR PROSITE; PS50969; FCP1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000257200}.
FT DOMAIN 674..832
FT /note="FCP1 homology"
FT /evidence="ECO:0000259|PROSITE:PS50969"
FT REGION 72..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 620..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..116
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..131
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..209
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..399
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT SITE 740
FT /note="Transition state stabilizer"
FT /evidence="ECO:0000256|PIRSR:PIRSR640078-3"
FT SITE 778
FT /note="Transition state stabilizer"
FT /evidence="ECO:0000256|PIRSR:PIRSR640078-3"
SQ SEQUENCE 849 AA; 95867 MW; 0AD15CBFE9914B81 CRC64;
MPTDQQSESS DFEPDELEVS CGSFGQYEMS NLGPECTEHL QYELSHQQCE SFDSEPDTST
EDFEQCEMSI ISDSGDSLDC GGEYCEYDEN QNQTECTNND DDDDDDSYEG EQNELEPSDE
ESSRSAEDSE DSPCVGDFFE THVYTKENSQ QVSTSDMSAD PSELCGNDNS ETSQEFEPTH
QSERNYENSF CSEEDGSSDC SSVETKSFKT CPDGSIPCDP CSDSSGESEK GAQEDSSDEQ
TQWESFEEDE EIQQSSINKS NEDQQKTPSV DIVIEDYFDL FDRADYHRHM FAQKQRYISC
FDGGDIHDHL YLEEEAQMHK AKNMYKSEEV NEEINVPQTD VCSEDAHEES SEEDTGQRDE
EWIGQSESSL TGDEDEENEA ETLASYTENS DEAEDDEAHF DEEPCALDVS EVCNEEDEAC
LSTGNEESMC APCAKEISVE GDAYEEEVYD TQEKYESLGG VTCTSDETEL TAADDKDEPA
PEDDVFIACS EMEPYWSLID DEEIGEFCEL DVEDYYAYQI KSIQSSIQQA LNGFIVGERS
YDASRNKRKD ALVSLEEEQA NPQECKTVTF QITEVIELNC SVVEETVDED CMLNEGSRQL
KLPSDIIHSV SKHAKIEGGD VAVKRTEDNK ASEQTRHSEE ESDDESCELC ECDYCIPPTE
QVPTQPLLPQ MKSNDAGKIC VVIDLDETLV HSSFKPVNNA DFIIPVEIDG TVHQVYVLKR
PHVDEFLKRM GELFECVLFT ASLSKYADPV SDLLDKWGAF RSRLFRESCV FHKGNYVKDL
SRLGRDLNKV IIIDNSPASY VFHPDNAVPV ASWFDDMSDT ELLDLIPFFE RLSKVDDIYE
ILKQQRTSS
//
